Simultaneous Down-Regulation of Intracellular MicroRNA-21 and hTERT mRNA Using AS1411-Functionallized Gold Nanoprobes to Achieve Targeted Anti-Tumor Therapy

Simultaneous Down-Regulation of Intracellular MicroRNA-21 and hTERT mRNA Using AS1411-Functionallized Gold Nanoprobes to Achieve Targeted Anti-Tumor Therapy

Telomerase presents over-expression in most cancer cells and has been used as a near-universal marker of cancer. Studies have revealed that inhibiting telomerase activity by utilizing oligonucleotides to down-regulate the expression of intracellular human telomerase reverse-transcriptase (hTERT) mRN...

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Bibliographic Details
Main Authors:	Qinghong Ji, Qiangqiang Yang, Mengyao Ou, Min Hong
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Nanomaterials
Subjects:	gene regulation microRNA-21 hTERT mRNA gold nanoparticles anti-tumor
Online Access:	https://www.mdpi.com/2079-4991/14/23/1956
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