Study on the preparation of stabilizer-free silymarin nanocrystals and its oral absorption mechanisms

Study on the preparation of stabilizer-free silymarin nanocrystals and its oral absorption mechanisms

Many researchers have studied the oral absorption mechanisms yet, however, considering stabilizers often participate in the absorption process of nanocrystals, these known mechanisms may be incorrect. Hence in this study, we aimed to explore the correct absorption mechanism of nanocrystals by perfor...

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Bibliographic Details
Main Authors: Liangxing Tu, Ping Han, Yongbing Sun, Yi Jin, Kaili Hu, Meng Cheng, Yisen Shao, Jianfang Feng, Fangying Yuan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Nanocrystals
Silymarin
High-pressure homogenization method
Physicochemical properties
Absorption mechanism
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000641
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http://www.sciencedirect.com/science/article/pii/S2590156724000641

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