Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma

Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma

Summary: Neuroblastoma exhibits two cellular phenotypes: therapy-sensitive adrenergic (ADRN) and therapy-resistant mesenchymal (MES). To understand treatment response, it is important to elucidate how these phenotypes impact the dynamics of cancer cell populations and whether they represent distinct...

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Bibliographic Details
Main Authors: Anuraag Bukkuri, Stina Andersson, Marina S. Mazariegos, Joel S. Brown, Emma U. Hammarlund, Sofie Mohlin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Biological sciences
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026580
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