Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma

Summary: Neuroblastoma exhibits two cellular phenotypes: therapy-sensitive adrenergic (ADRN) and therapy-resistant mesenchymal (MES). To understand treatment response, it is important to elucidate how these phenotypes impact the dynamics of cancer cell populations and whether they represent distinct...

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Bibliographic Details
Main Authors: Anuraag Bukkuri, Stina Andersson, Marina S. Mazariegos, Joel S. Brown, Emma U. Hammarlund, Sofie Mohlin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026580
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