Impact of Nintedanib on tumor angiogenesis and vascular normalization in a mouse model of colorectal cancer

Abstract Background For many solid types of cancer including colorectal cancer treatment with the VEGF antibody bevacizumab as anti-angiogenic treatment has become standard of care. Nevertheless, long-term treatment with anti-angiogenic drugs in combination with other treatment modalities or alone c...

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Bibliographic Details
Main Authors: Naita M. Wirsik, Jens M. Seeger, Thomas Schmidt, Frank Hilberg, Hans F. Fuchs, Christiane J. Bruns, Oliver Coutelle, Hamid Kashkar, Lars M. Schiffmann
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-03071-4
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