Influence of Citrobacter freundii on NINJ2 Expression and Oxaliplatin Resistance in Colorectal Cancer

Influence of Citrobacter freundii on NINJ2 Expression and Oxaliplatin Resistance in Colorectal Cancer

ABSTRACT Background Oxaliplatin, a third‐generation platinum‐based chemotherapeutic agent, is widely used in the treatment of colorectal cancer (CRC). However, some patients do not respond effectively to oxaliplatin, and intrinsic resistance to the drug poses a significant challenge. Recent studies...

Full description

Saved in:

Bibliographic Details
Main Authors:	Reio Ueta, Hiroo Imai, Ken Saijo, Yoshifumi Kawamura, Shuto Kodera, Chikashi Ishioka
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Series:	Cancer Medicine
Subjects:	bacterial culture filtrate Citrobacter freundii colon cancer gut microbiome oxaliplatin
Online Access:	https://doi.org/10.1002/cam4.70940
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Citrobacter freundii Brain Abscess in a Preterm Infant: A Case Report and Literature Review
by: Nishad Plakkal, et al.
Published: (2013-04-01)

Cathelicidin regulates goblet cell mucus secretion and mucus-associated proteins in Citrobacter rodentium-induced colitis
by: Niloofar Mirzadzare, et al.
Published: (2025-12-01)

Epidemiology, phylogeny and genetic characterization of carbapenem-resistant Citrobacter spp. from 5 hospitals in China
by: Qiang Zhao, et al.
Published: (2025-05-01)

Bioremediation Activity of Pb (II) Resistance Citrobacter sp. MKH2 Isolated from Heavy Metal Contaminated Sites in Iran
by: M. Mohseni
Published: (2014-06-01)

Emerging trends of nosocomial Citrobacter species surgical wound infection: concern for infection control
by: B Thapa, et al.
Published: (2012-01-01)

Emerging trends of nosocomial Citrobacter species surgical wound infection: concern for infection control
by: B Thapa, et al.
Published: (2012-01-01)

Extended spectrum AmpC and metallo-beta-lactamases in Serratia and Citrobacter spp. in a disc approximation assay
by: Meher Rizvi, et al.
Published: (2009-05-01)

Isolation and algicidal characteristics of Citrobacter sp. strain N10
by: SUN Pengfei, et al.
Published: (2013-11-01)

Characterization of Citrobacter sp. line 328 as a source of Vi for a Vi-CRM197 glycoconjugate vaccine against Salmonella Typhi
by: Simona Rondini, et al.
Published: (2012-11-01)

Activity of LpxC inhibitors on carbapenemase-producing Citrobacter spp. clinical isolates
by: Víctor Vinuesa, et al.
Published: (2025-09-01)

A rare case of localized peliosis hepatis during adjuvant chemotherapy including oxaliplatin mimicking a liver metastasis of colon cancer
by: Akira Dejima, et al.
Published: (2023-11-01)

Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis
by: Amirali Azimi, et al.
Published: (2024-12-01)

Dissolving microneedles enabled delivery of Oxaliplatin- sodium butyrate loaded outer membrane vesicles against rectal cancer
by: Chu Jian, et al.
Published: (2025-08-01)

Investigating the cytotoxic effect of aqueous extract of Peganum harmala on oxaliplatin-resistant HCT116 cell line and evaluating BAX gene expression
by: Zahra Salimizadeh, et al.
Published: (2025-03-01)

Phosphorylation of KIAA1429 promotes oxaliplatin resistance through activating the FZD7-Wnt signaling in BRAFV600E-mutated colorectal cancer
by: Taixuan Wan, et al.
Published: (2025-07-01)

Overexpression of Protein Kinase C iota as a prognostic marker and its role in oxaliplatin resistance in colorectal cancer
by: Xuankai Liao, et al.
Published: (2025-08-01)

Genomic characterization of a multidrug-resistant Citrobacter portucalensis isolate co-harboring blaKPC–2 and blaNDM–1 on distinct plasmids
by: Junwei Huang, et al.
Published: (2025-07-01)

Syndrome of inappropriate antidiuretic hormone secretion in a patient with colon cancer using CAPOX plus bevacizumab therapy: a case report
by: Masanobu Uchiyama, et al.
Published: (2025-07-01)

A pathological complete response by chemotherapy with S-1 and oxaliplatin for a locally advanced duodenal adenocarcinoma in Lynch syndrome: a case report
by: Satoshi Yasuda, et al.
Published: (2019-10-01)

Efficacy and safety of oxaliplatin-based hyperthermic intraperitoneal chemotherapy with secondary cytoreduction for platinum resistant recurrent ovarian cancer: A single-center retrospective cohort study
by: Hua-Hsi Wu, et al.
Published: (2025-08-01)

Oxygen vacancy-engineered bimetallic nanozymes for disrupting electron transport chain and synergistic multi-enzyme activity to reverse oxaliplatin resistance in colorectal cancer
by: Dong Zhong, et al.
Published: (2025-05-01)

Predictive factors for efficacy of oxaliplatin-based chemotherapy in advanced well-differentiated neuroendocrine tumors: an observational cohort study and meta-analysis
by: Jian Wang, et al.
Published: (2025-05-01)

USF1-activated hsa_circ_0076691 induces oxaliplatin resistance via facilitating FGF9 expression in miR-589-3p-dependent manners
by: Lingyu Tang, et al.
Published: (2025-08-01)

Dendrosomal Curcumin Nanoformulation induces apoptosis via Bax/Bcl-2 in human ovarian cancer OVCAR3 cells
by: Marziyeh Alizadeh Zarei, et al.
Published: (2025-01-01)

Efficacy and Safety of Hepatic Artery Infusion Chemotherapy Combined with Donafenib and Camrelizumab in the Treatment of Patients with Unresectable Hepatocellular Carcinoma: A Retrospective, Single-Arm Study
by: Wu C, et al.
Published: (2025-07-01)

Short‐Term Results of the SONCAR Study: Optimized Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients
by: Rongxin Zhang, et al.
Published: (2025-08-01)

Clinicopathological features and treatment outcomes of patients with fibrolamellar hepatocellular carcinoma: a retrospective multicenter study
by: Ali Kaan Güren, et al.
Published: (2025-07-01)

NINJ1 and MMP9: potential biomarkers for intracranial atherosclerosis plaque vulnerability
by: Xiao-lian Wei, et al.
Published: (2025-04-01)

Drug-Induced Liver Injury and the Likelihood of Hepatocellular Carcinoma During Chemotherapy for Colorectal Cancer (Meta-Analysis)
by: T. N. Garmanova, et al.
Published: (2025-08-01)

Team coordination in laparoscopic left hemicolectomy
by: Ge Xinbin, et al.
Published: (2024-08-01)

Application of the formula for estimating glomerular filtration rate in the elderly population
by: Yang Dan, et al.
Published: (2025-04-01)

Effects of national volume-based procurement policy on the usage and expenditure of platinum antineoplastic drugs in China: an interrupted time series study
by: Xihui Yu, et al.
Published: (2025-08-01)

Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line stimulated with live probiotic bacteria
by: Akira Sen, et al.
Published: (2025-07-01)

The description of broadband matching and frequency-selective chains by means of the generalised matrix of dispersion
by: A. A. Svirydzenka
Published: (2019-06-01)

Research advances of shrunken pore syndrome
by: Zhang Pei, et al.
Published: (2022-03-01)

Filtration in Pharmaceutical Industries and Role of Textile
by: Akhtarul Islam Amjad
Published: (2022-10-01)

Significance of FXa and its receptor PAR2 for the growth of colon cancer cells in vitro and in vivo
by: Ulrike Meyer, et al.
Published: (2025-07-01)

A Comprehensive Software and Database Management System for Glomerular Filtration Rate Estimation by Radionuclide Plasma Sampling and Serum Creatinine Methods
by: Ashish Jha
Published: (2015-04-01)

Ischemic Changes in the Mucous Membrane of the Transverse Colon as a Complication of Acute Pancreatitis
by: D. A. Semenov, et al.
Published: (2023-02-01)

EVOLUTION OF DEFORESTATION AND NATURAL RESOURCES DEGRADATION IN RONDONIA
by: Joiada Moreira da Silva, et al.
Published: (2005-05-01)