Cardiac involvement in familial Mediterranean fever

The paper deals with contemporary issues of cardiac involvement at various stages of periodic disease (familial Mediterranean fever). It is supposed that inflammation during acute attacks, in between attacks and in case of amyloidosis development is the main pathologic factor leading to functional a...

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Main Authors: A. Yu. Gasparyan, A. H. Petrosyan
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2007-12-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1444
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author A. Yu. Gasparyan
A. H. Petrosyan
author_facet A. Yu. Gasparyan
A. H. Petrosyan
author_sort A. Yu. Gasparyan
collection DOAJ
description The paper deals with contemporary issues of cardiac involvement at various stages of periodic disease (familial Mediterranean fever). It is supposed that inflammation during acute attacks, in between attacks and in case of amyloidosis development is the main pathologic factor leading to functional and organic heart disturbances in this disease. Shifts of some immunological parameters, along with activation of sympatho!adrenal and other systems and organs, are considered as pathogenic factors predisposing to exhaustion of heart functional reserves. Based on the pathomorphological data, it is possible to claim that myocardial dysfunction, due to microvascular pathology and amyloid sedimentation, is a characteristic feature of the disease, though involvement of other heart structures is not excluded. The main directions for cardiac involvement diagnostics are described and comparatively analyzed.
format Article
id doaj-art-c7299df86cdb4f1e99f17a3cf8109a29
institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2007-12-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-c7299df86cdb4f1e99f17a3cf8109a292025-08-20T03:57:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-12-01661171241154Cardiac involvement in familial Mediterranean feverA. Yu. Gasparyan0A. H. Petrosyan1M. Geratsi Yerevan State Medical University, YerevanM. Geratsi Yerevan State Medical University, YerevanThe paper deals with contemporary issues of cardiac involvement at various stages of periodic disease (familial Mediterranean fever). It is supposed that inflammation during acute attacks, in between attacks and in case of amyloidosis development is the main pathologic factor leading to functional and organic heart disturbances in this disease. Shifts of some immunological parameters, along with activation of sympatho!adrenal and other systems and organs, are considered as pathogenic factors predisposing to exhaustion of heart functional reserves. Based on the pathomorphological data, it is possible to claim that myocardial dysfunction, due to microvascular pathology and amyloid sedimentation, is a characteristic feature of the disease, though involvement of other heart structures is not excluded. The main directions for cardiac involvement diagnostics are described and comparatively analyzed.https://cardiovascular.elpub.ru/jour/article/view/1444familial mediterranean feverheartamyloidosisdiagnosticspathomorphologyechocardiography
spellingShingle A. Yu. Gasparyan
A. H. Petrosyan
Cardiac involvement in familial Mediterranean fever
Кардиоваскулярная терапия и профилактика
familial mediterranean fever
heart
amyloidosis
diagnostics
pathomorphology
echocardiography
title Cardiac involvement in familial Mediterranean fever
title_full Cardiac involvement in familial Mediterranean fever
title_fullStr Cardiac involvement in familial Mediterranean fever
title_full_unstemmed Cardiac involvement in familial Mediterranean fever
title_short Cardiac involvement in familial Mediterranean fever
title_sort cardiac involvement in familial mediterranean fever
topic familial mediterranean fever
heart
amyloidosis
diagnostics
pathomorphology
echocardiography
url https://cardiovascular.elpub.ru/jour/article/view/1444
work_keys_str_mv AT ayugasparyan cardiacinvolvementinfamilialmediterraneanfever
AT ahpetrosyan cardiacinvolvementinfamilialmediterraneanfever