A Review of Non-Linear Optical Imaging Techniques for Cancer Detection
The World Health Organization (WHO) cancer agency predicts that more than 35 million cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate. Currently, the main cancers diagnosed are breast, lung, and colorectal. There is no standardized tool for cancer diagnoses; initial...
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MDPI AG
2024-10-01
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| Series: | Optics |
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| Online Access: | https://www.mdpi.com/2673-3269/5/4/31 |
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| author | Francisco J. Ávila |
| author_facet | Francisco J. Ávila |
| author_sort | Francisco J. Ávila |
| collection | DOAJ |
| description | The World Health Organization (WHO) cancer agency predicts that more than 35 million cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate. Currently, the main cancers diagnosed are breast, lung, and colorectal. There is no standardized tool for cancer diagnoses; initially, clinical procedures are guided by the patient symptoms and usually involve biochemical blood tests, imaging, and biopsy. Label-free non-linear optical approaches are promising tools for tumor imaging, due to their inherent non-invasive biosafe contrast mechanisms and the ability to monitor collagen-related disorders, and biochemical and metabolic changes during cancer progression. In this review, the main non-linear microscopy techniques are discussed, according to three main contrast mechanisms: biochemical, metabolic, and structural imaging. |
| format | Article |
| id | doaj-art-c71a5590a6b2443ea8c73fc70c326e45 |
| institution | Kabale University |
| issn | 2673-3269 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Optics |
| spelling | doaj-art-c71a5590a6b2443ea8c73fc70c326e452024-12-27T14:44:47ZengMDPI AGOptics2673-32692024-10-015441643310.3390/opt5040031A Review of Non-Linear Optical Imaging Techniques for Cancer DetectionFrancisco J. Ávila0Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, SpainThe World Health Organization (WHO) cancer agency predicts that more than 35 million cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate. Currently, the main cancers diagnosed are breast, lung, and colorectal. There is no standardized tool for cancer diagnoses; initially, clinical procedures are guided by the patient symptoms and usually involve biochemical blood tests, imaging, and biopsy. Label-free non-linear optical approaches are promising tools for tumor imaging, due to their inherent non-invasive biosafe contrast mechanisms and the ability to monitor collagen-related disorders, and biochemical and metabolic changes during cancer progression. In this review, the main non-linear microscopy techniques are discussed, according to three main contrast mechanisms: biochemical, metabolic, and structural imaging.https://www.mdpi.com/2673-3269/5/4/31cancertumor tissuespontaneous Raman scatteringstimulated Raman scatteringcoherent anti-stokes Raman scatteringtwo-photon excitation |
| spellingShingle | Francisco J. Ávila A Review of Non-Linear Optical Imaging Techniques for Cancer Detection Optics cancer tumor tissue spontaneous Raman scattering stimulated Raman scattering coherent anti-stokes Raman scattering two-photon excitation |
| title | A Review of Non-Linear Optical Imaging Techniques for Cancer Detection |
| title_full | A Review of Non-Linear Optical Imaging Techniques for Cancer Detection |
| title_fullStr | A Review of Non-Linear Optical Imaging Techniques for Cancer Detection |
| title_full_unstemmed | A Review of Non-Linear Optical Imaging Techniques for Cancer Detection |
| title_short | A Review of Non-Linear Optical Imaging Techniques for Cancer Detection |
| title_sort | review of non linear optical imaging techniques for cancer detection |
| topic | cancer tumor tissue spontaneous Raman scattering stimulated Raman scattering coherent anti-stokes Raman scattering two-photon excitation |
| url | https://www.mdpi.com/2673-3269/5/4/31 |
| work_keys_str_mv | AT franciscojavila areviewofnonlinearopticalimagingtechniquesforcancerdetection AT franciscojavila reviewofnonlinearopticalimagingtechniquesforcancerdetection |