A Review of Non-Linear Optical Imaging Techniques for Cancer Detection
The World Health Organization (WHO) cancer agency predicts that more than 35 million cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate. Currently, the main cancers diagnosed are breast, lung, and colorectal. There is no standardized tool for cancer diagnoses; initial...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-10-01
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| Series: | Optics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-3269/5/4/31 |
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| Summary: | The World Health Organization (WHO) cancer agency predicts that more than 35 million cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate. Currently, the main cancers diagnosed are breast, lung, and colorectal. There is no standardized tool for cancer diagnoses; initially, clinical procedures are guided by the patient symptoms and usually involve biochemical blood tests, imaging, and biopsy. Label-free non-linear optical approaches are promising tools for tumor imaging, due to their inherent non-invasive biosafe contrast mechanisms and the ability to monitor collagen-related disorders, and biochemical and metabolic changes during cancer progression. In this review, the main non-linear microscopy techniques are discussed, according to three main contrast mechanisms: biochemical, metabolic, and structural imaging. |
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| ISSN: | 2673-3269 |