The 14-bp insertion/deletion as a promising gene polymorphism to understand cancer risk: Evidence from a systematic review and comprehensive meta-analysis

The 14-bp insertion/deletion as a promising gene polymorphism to understand cancer risk: Evidence from a systematic review and comprehensive meta-analysis

Background: HLA-G is associated with cancer cell escape. The 3′UTR polymorphism is involved in the regulation of membrane-bound HLA-G and soluble HLA-G proteins. The aim of our study was to assess the association of the HLA-G 14-bp insertion (I)/deletion (D) polymorphism with cancer susceptibility a...

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Bibliographic Details
Main Authors: Kalthoum Tizaoui, Mohamed Ali Ayadi, Ines Zemni, Abdel Halim Harrath, Roberta Rizzo, Nadia Boujelbene, Inès Zidi
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
HLA-G gene
14-bp I/D polymorphism
Cancer
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024157714
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