Protective effect of TNF-α inhibitor on diabetic nephropathy in rats

Protective effect of TNF-α inhibitor on diabetic nephropathy in rats

Objective To explore the protective effect of TNF-α inhibitor on diabetic tubulointerstitium damage, and its related mechanism. Methods The rat model of type I diabetes was established by using STZ induction method, and the rats were divided into model group(without medication), IgG treatment group(...

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Main Authors: HOU Jia-sheng, ZHAO Ting, ZHOU Lu, LIU Xuan-chen, LIN Ying-ying, ZHANG Guang-yuan, ZHAO Qing, YIN Jian-yong, LIANG Ru-lian, CHENG Dong-sheng, WU Rui, WANG Nian-song, WANG Feng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2019-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
TNF-α
Diabetic nephropathy
Tubulointerstitium damage
NLRP3 inflammasome
Online Access:http://www.lcszb.com/thesisDetails?columnId=57912771&Fpath=home&index=0
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