Modulation of Sel1L can alleviate altered ER homeostasis towards white matter damage in CKD-stroke complex

Modulation of Sel1L can alleviate altered ER homeostasis towards white matter damage in CKD-stroke complex

Abstract Stroke is one of the major causes of mortality and long-term disability worldwide. Chronic-kidney-disease (CKD) is a condition where patients have shown increased vulnerability to stroke with poor functional and cognitive outcomes. Impaired cerebral autoregulation in CKD patients may impose...

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Main Authors: Aishika Datta, Priti Patale, Debarati Ghosh, Priya Jagtap, Jinagna Shah, Mounika Katamneni, Anita Kumari, Nikita Malik, Gautam Karmarkar, Anirban Barik, Bijoyani Ghosh, Pooja Dhakne, Vinod Pathulothu, Deepaneeta Sarmah, Harpreet Kaur, Nikita Rana, Rajeshwari Rathod, Anupom Borah, Pinaki Sengupta, Pallab Bhattacharya
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08100-0
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