A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus
Background and objectives. Coronary angioplasty is a common intervention for improving cardiac function postmyocardial infarction. However, the impact of this procedure in patients with type-2 diabetes mellitus (T2DM) compared to those without diabetes remains less understood. Material and methods....
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Amaltea Medical Publishing House
2024-09-01
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| Series: | Romanian Medical Journal |
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| Online Access: | https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-11.pdf |
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| author | Sava Nanda Gopal Hanumath Prasad Yallanki Kaldindu Lakshmi Priya Kannan R. |
| author_facet | Sava Nanda Gopal Hanumath Prasad Yallanki Kaldindu Lakshmi Priya Kannan R. |
| author_sort | Sava Nanda Gopal |
| collection | DOAJ |
| description | Background and objectives. Coronary angioplasty is a common intervention for improving cardiac function postmyocardial infarction. However, the impact of this procedure in patients with type-2 diabetes mellitus (T2DM) compared to those without diabetes remains less understood. Material and methods. This study included 50 patients who underwent coronary angioplasty post-myocardial infarction. Patients were divided into two groups based on the presence (Group A) or absence (Group B) of T2DM, with 6 patients in each group. We assessed left ventricular function using echocardiography, focusing on ejection fraction and wall motion score, at baseline, and at 1, 3, and 6 months post-angioplasty. Additional data on clinical outcomes, functional status, cardiac biomarkers, medication use, comorbid condition management, and hemodynamic measurements were also collected. Results. Both groups showed improvement in left ventricular function post-angioplasty, with no significant difference in ejection fraction and wall motion score between the two groups at each follow-up. Clinical outcomes, functional status, and biomarker levels were comparable between groups. Medication compliance was high in both groups. The control of comorbid conditions and hemodynamic stability post-angioplasty were similarly maintained in both diabetic and nondiabetic patients. Conclusion. Coronary angioplasty positively impacts left ventricular function in post-myocardial infarction patients, irrespective of the presence of T2DM. Both diabetic and non-diabetic patients demonstrated similar improvements in cardiac function and overall clinical outcomes, suggesting that angioplasty is an effective intervention for post-myocardial infarction patients regardless of their diabetes status. Further studies with larger sample sizes are recommended to validate these findings. |
| format | Article |
| id | doaj-art-c625561ec3064c708030362c6adf4bef |
| institution | Kabale University |
| issn | 1220-5478 2069-606X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Medical Journal |
| spelling | doaj-art-c625561ec3064c708030362c6adf4bef2025-01-07T13:23:38ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2024-09-0171327928310.37897/RMJ.2024.3.11A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitusSava Nanda Gopal0Hanumath Prasad Yallanki1Kaldindu Lakshmi Priya2Kannan R.3Department of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaBackground and objectives. Coronary angioplasty is a common intervention for improving cardiac function postmyocardial infarction. However, the impact of this procedure in patients with type-2 diabetes mellitus (T2DM) compared to those without diabetes remains less understood. Material and methods. This study included 50 patients who underwent coronary angioplasty post-myocardial infarction. Patients were divided into two groups based on the presence (Group A) or absence (Group B) of T2DM, with 6 patients in each group. We assessed left ventricular function using echocardiography, focusing on ejection fraction and wall motion score, at baseline, and at 1, 3, and 6 months post-angioplasty. Additional data on clinical outcomes, functional status, cardiac biomarkers, medication use, comorbid condition management, and hemodynamic measurements were also collected. Results. Both groups showed improvement in left ventricular function post-angioplasty, with no significant difference in ejection fraction and wall motion score between the two groups at each follow-up. Clinical outcomes, functional status, and biomarker levels were comparable between groups. Medication compliance was high in both groups. The control of comorbid conditions and hemodynamic stability post-angioplasty were similarly maintained in both diabetic and nondiabetic patients. Conclusion. Coronary angioplasty positively impacts left ventricular function in post-myocardial infarction patients, irrespective of the presence of T2DM. Both diabetic and non-diabetic patients demonstrated similar improvements in cardiac function and overall clinical outcomes, suggesting that angioplasty is an effective intervention for post-myocardial infarction patients regardless of their diabetes status. Further studies with larger sample sizes are recommended to validate these findings.https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-11.pdfcoronary angioplastyleft ventricular functionmyocardial infarctiontype-2 diabetes mellitusechocardiography |
| spellingShingle | Sava Nanda Gopal Hanumath Prasad Yallanki Kaldindu Lakshmi Priya Kannan R. A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus Romanian Medical Journal coronary angioplasty left ventricular function myocardial infarction type-2 diabetes mellitus echocardiography |
| title | A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus |
| title_full | A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus |
| title_fullStr | A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus |
| title_full_unstemmed | A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus |
| title_short | A comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type-2 diabetes mellitus |
| title_sort | comparative study on the effect of coronary angioplasty on left ventricular function in post myocardial infarction among patients with and without type 2 diabetes mellitus |
| topic | coronary angioplasty left ventricular function myocardial infarction type-2 diabetes mellitus echocardiography |
| url | https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-11.pdf |
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