The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm
Objective: To evaluate the effect of biofilm layer on polyp formation in nasal polyposis by comparing the amount of biofilm layer on polyp tissue and the normal mucosa. Material and Methods: This study is a prospective study. 14 patients who underwent functional endoscopic sinus surgery (FESS) for...
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Selcuk University Press
2022-02-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2046314 |
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| author | Kazım Bozdemir Yuce İslamoglu Nurcan Özyurt Koçakoğlu Serkan Şerifler Selami Candan Bülent Ulusoy Elif Ersoy Çallıoğlu |
| author_facet | Kazım Bozdemir Yuce İslamoglu Nurcan Özyurt Koçakoğlu Serkan Şerifler Selami Candan Bülent Ulusoy Elif Ersoy Çallıoğlu |
| author_sort | Kazım Bozdemir |
| collection | DOAJ |
| description | Objective: To evaluate the effect of biofilm layer on polyp formation in nasal polyposis by comparing the amount of biofilm layer on polyp tissue and the normal mucosa.
Material and Methods: This study is a prospective study. 14 patients who underwent functional endoscopic sinus surgery (FESS) for nasal polyposis were evaluated. Patients were had no history of previous FESS. Tissue samples were obtained from lower turbinate (Group 1 n:14) and from nasal polyp (Group 2, n:14) of the same nasal cavity. Biofilm presence was identified using scanning electron microscopic (SEM) morphological findings. In biofilm positive samples, the presence of biofilm in less than 25% of the surface area was classified as (+), between 25-50% as (++) , and over 50% as (+++).
Results: In Group 2, with SEM imaging, (+++) biofilm presence was detected in 9 patients and (++) biofilm was detected in 5 patients. In Group 1, no biofilm was detected 8 patients, while; (+++), (++), and (+) biofilm presence was detected in 1, 2, and 3 patients respectively. Significant difference was found between group 1 and group 2 with respect to the amount of biofilm according to SEM (p =0.000).
Conclusion: In samples, statistically significant difference was found between polyp tissue and normal mucosa in terms of the amount of biofilm. However, further studies with larger patient series are required in order to reach a definitive conclusion on the effect of biofilm on pathogenesis of polyp. |
| format | Article |
| id | doaj-art-c603de6757c74857a26b05eefddef5da |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2022-02-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-c603de6757c74857a26b05eefddef5da2025-01-02T21:15:04ZengSelcuk University PressGenel Tıp Dergisi2602-37412022-02-01321363810.54005/geneltip.1014726154The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of BiofilmKazım Bozdemir0Yuce İslamoglu1Nurcan Özyurt Koçakoğlu2Serkan Şerifler3Selami Candan4Bülent Ulusoy5Elif Ersoy Çallıoğlu6YILDIRIM BEYAZIT ÜNİVERSİTESİAnkara Bilkent City Hospital, Otorhinolaryngology Clinic, AnkaraGAZI UNIVERSITY, FACULTY OF SCIENCEYILDIRIM BEYAZIT UNIVERSITYGAZI UNIVERSITY, FACULTY OF SCIENCESELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİAnkara Bilkent City Hospital, Otorhinolaryngology Clinic, AnkaraObjective: To evaluate the effect of biofilm layer on polyp formation in nasal polyposis by comparing the amount of biofilm layer on polyp tissue and the normal mucosa. Material and Methods: This study is a prospective study. 14 patients who underwent functional endoscopic sinus surgery (FESS) for nasal polyposis were evaluated. Patients were had no history of previous FESS. Tissue samples were obtained from lower turbinate (Group 1 n:14) and from nasal polyp (Group 2, n:14) of the same nasal cavity. Biofilm presence was identified using scanning electron microscopic (SEM) morphological findings. In biofilm positive samples, the presence of biofilm in less than 25% of the surface area was classified as (+), between 25-50% as (++) , and over 50% as (+++). Results: In Group 2, with SEM imaging, (+++) biofilm presence was detected in 9 patients and (++) biofilm was detected in 5 patients. In Group 1, no biofilm was detected 8 patients, while; (+++), (++), and (+) biofilm presence was detected in 1, 2, and 3 patients respectively. Significant difference was found between group 1 and group 2 with respect to the amount of biofilm according to SEM (p =0.000). Conclusion: In samples, statistically significant difference was found between polyp tissue and normal mucosa in terms of the amount of biofilm. However, further studies with larger patient series are required in order to reach a definitive conclusion on the effect of biofilm on pathogenesis of polyp.https://dergipark.org.tr/tr/download/article-file/2046314biofilmnasal polypmicroscopy, electron, scanningbiyofilmnazal polipscanning-electron mikroskopi |
| spellingShingle | Kazım Bozdemir Yuce İslamoglu Nurcan Özyurt Koçakoğlu Serkan Şerifler Selami Candan Bülent Ulusoy Elif Ersoy Çallıoğlu The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm Genel Tıp Dergisi biofilm nasal polyp microscopy, electron, scanning biyofilm nazal polip scanning-electron mikroskopi |
| title | The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm |
| title_full | The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm |
| title_fullStr | The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm |
| title_full_unstemmed | The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm |
| title_short | The Evaluation of The Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm |
| title_sort | evaluation of the relation between nasal polyp etiopathogenesis and the amount of biofilm |
| topic | biofilm nasal polyp microscopy, electron, scanning biyofilm nazal polip scanning-electron mikroskopi |
| url | https://dergipark.org.tr/tr/download/article-file/2046314 |
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