Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis

Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis

Abstract Background The regenerative potential of mesenchymal stromal/stem cells (MSCs) has been extensively studied in clinical trials in the past decade. However, despite the promising regenerative properties documented in preclinical studies, for instance in osteoarthritis (OA), the therapeutic t...

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Main Authors: Damien Veret, Gautier Tejedor, Esther Perez, Alison Chomette, Maylis Farno, Rosanna Ferreira-Lopez, Louis Dagneaux, Yves-Marie Pers, Christian Jorgsensen, Claire Gondeau, Jean-Marc Brondello
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal/stem cells
Rapamycin
Regenerative medicine
Osteoarthritis
Online Access:https://doi.org/10.1186/s13287-024-04090-8
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