CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection

CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection

Abstract The blood vessel network is heavily impacted by SARS-CoV-2 infection. How SARS-CoV-2 contributes to vascular inflammation and whether epithelio-endothelial cross-talk is involved remain unclear. We investigated in detail the interaction between SARS-CoV-2 and the vasculature using 2D and 3D...

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Main Authors: Chaillot Laura, Blondot Marie-Lise, Recordon-Pinson Patricia, Pellegrin Isabelle, Boizard-Moracchini Andrea, Sliusar Myroslava, Leboucq Teo, Pujol Nadege, Andreola Marie-Line, Bonnet Fabrice, Recher Gaelle, Andrique Laetitia, Nassoy Pierre, Mathivet Thomas, Bikfalvi Andreas
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Endothelium
SARS-CoV-2
Chemokines
CXCL10
Online Access:https://doi.org/10.1038/s41598-025-08329-z
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