Nature or nurture: genetic and environmental predictors of adiposity gain in adultsResearch in context

Nature or nurture: genetic and environmental predictors of adiposity gain in adultsResearch in context

Summary: Background: Previous prediction models for adiposity gain have not yet achieved sufficient predictive ability for clinical relevance. We investigated whether traditional and genetic factors accurately predict adiposity gain. Methods: A 5-year gain of ≥5% in body mass index (BMI) and waist-...

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Main Authors: Laia Peruchet-Noray, Niki Dimou, Reynalda Cordova, Emma Fontvieille, Anna Jansana, Quan Gan, Marie Breeur, Hansjörg Baurecht, Patricia Bohmann, Julian Konzok, Michael J. Stein, Christina C. Dahm, Nuno R. Zilhão, Lene Mellemkjær, Anne Tjønneland, Rudolf Kaaks, Verena Katzke, Elif Inan-Eroglu, Matthias B. Schulze, Giovanna Masala, Sabina Sieri, Vittorio Simeon, Giuseppe Matullo, Esther Molina-Montes, Pilar Amiano, María-Dolores Chirlaque, Alba Gasque, Joshua Atkins, Karl Smith-Byrne, Pietro Ferrari, Vivian Viallon, Antonio Agudo, Marc J. Gunter, Catalina Bonet, Heinz Freisling, Robert Carreras-Torres
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:EBioMedicine
Subjects:
Adiposity gain
Prediction
Polygenic risk scores
Environmental factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424005462
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http://www.sciencedirect.com/science/article/pii/S2352396424005462

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