An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

IntroductionArthrosamid®, Arthramid®, Bulkamid®, and Mictamid® are products for the management of osteoarthritis and female urinary incontinence. All four products include the same injectable hydrogel consisting of 2.5% crosslinked polyacrylamide termed 2.5 iPAAG that is polymerized from the neuroto...

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Bibliographic Details
Main Authors: Peter S. Walmod, Philip Kusk, Nina Jøhnk, Ieva Ankorina-Stark, Anthony Essex
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Toxicology
Subjects:
acrylamide
Arthramid®
Arthrosamid®
Bulkamid®
Mictamid®
neurotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2025.1585430/full
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