Three-dimensional conformal therapy vs. intensity modulated radiation therapy in GBM: survival, dosimetry, and side effects a systematic review and meta-analysis

Three-dimensional conformal therapy vs. intensity modulated radiation therapy in GBM: survival, dosimetry, and side effects a systematic review and meta-analysis

BackgroundGlioblastoma multiforme (GBM) is an aggressive brain tumor with a poor prognosis, often managed with radiotherapy. Two primary modalities, three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT), differ in their precision and impact on survival, side e...

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Bibliographic Details
Main Authors: Omar Freihat, David Sipos, Reham Kotb, Maria Aamir, Dóra Solymosi, Kristóf Gál, Simon Mihály, Arpad Kovacs
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Physics
Subjects:
glioblastoma multiforme (GBM)
intensity-modulated radiotherapy (IMRT)
three-dimensional conformal radiotherapy (3D-CRT)
overall survival (OS)
organs at risk glioblastoma multiforme (GBM)
dosimetry
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2025.1632620/full
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