Impact of TP53 mutations on the efficacy of CAR-T cell therapy in cancer
The efficacy of chimeric antigen receptor (CAR)-T therapy may not match initial expectations due to the influence of multiple circumstances, some of which cannot be predicted. CAR-T treatment groups include high-risk patients, particularly those with TP53 mutations. A significant body of research ha...
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| Main Authors: | Regina Mirgayazova, Raniya Khadiullina, Maria Filimonova, Vitaly Chasov, Emil Bulatov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Open Exploration Publishing Inc.
2024-12-01
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| Series: | Exploration of Immunology |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/Journals/ei/Article/1003176 |
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