Impact of TP53 mutations on the efficacy of CAR-T cell therapy in cancer

The efficacy of chimeric antigen receptor (CAR)-T therapy may not match initial expectations due to the influence of multiple circumstances, some of which cannot be predicted. CAR-T treatment groups include high-risk patients, particularly those with TP53 mutations. A significant body of research ha...

Full description

Saved in:
Bibliographic Details
Main Authors: Regina Mirgayazova, Raniya Khadiullina, Maria Filimonova, Vitaly Chasov, Emil Bulatov
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-12-01
Series:Exploration of Immunology
Subjects:
Online Access:https://www.explorationpub.com/Journals/ei/Article/1003176
Tags: Add Tag
No Tags, Be the first to tag this record!