Automated radiofluorination of HER2 single domain antibody: the road towards the clinical translation of [18F]FB-HER2 sdAb

Abstract Background With the next generation of Human Epidermal Growth Factor Receptor 2 (HER2) -targeting therapies, such as antibody–drug conjugates, showing benefit in “HER2 low” and even “HER2 ultralow” patients, the need for novel methods to quantify HER2 expression accurately becomes even more...

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Bibliographic Details
Main Authors: Herlinde Dierick, Laurent Navarro, Sonja Van den Block, Jelena Saliën, Tony Lahoutte, Vicky Caveliers, Jessica Bridoux
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Online Access:https://doi.org/10.1186/s41181-024-00306-7
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