Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa
Emmanuel Kimaro,1 Eveline Thobias Konje,2 Amani Thomas Mori,3 Benson Richard Kidenya,4 Eliangiringa Kaale5,6 1Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania; 2Department of Biostatistics and Epidemiol...
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Dove Medical Press
2025-08-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
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| author | Kimaro E Konje ET Mori AT Kidenya BR Kaale E |
| author_facet | Kimaro E Konje ET Mori AT Kidenya BR Kaale E |
| author_sort | Kimaro E |
| collection | DOAJ |
| description | Emmanuel Kimaro,1 Eveline Thobias Konje,2 Amani Thomas Mori,3 Benson Richard Kidenya,4 Eliangiringa Kaale5,6 1Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania; 2Department of Biostatistics and Epidemiology, School of Public Health, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania; 3Department of Global Public Health and Primary Care, Section for Ethics and Health Economics, University of Bergen, Bergen, Norway; 4Department of Biochemistry and Molecular Biology, Catholic University of Health and Allied Sciences (CUHAS), School of Medicine, Mwanza, Tanzania; 5Pharm R&D Laboratory, School of Pharmacy, Muhimbili University of Health and Allied Sciences (MUHAS), Dar Es Salaam, Tanzania; 6Department of Medicinal Chemistry, Muhimbili University of Health and Allied Sciences (MUHAS), School of Pharmacy, Dar Es Salaam, TanzaniaCorrespondence: Emmanuel Kimaro, Email ekimaro12@gmail.comAbstract: Insulin stability is a critical yet underexplored factor affecting diabetes outcomes in Sub-Saharan Africa (SSA). High ambient temperatures, unreliable refrigeration, and weak regulatory oversight may compromise insulin quality during storage and use. Patients often rely on traditional, non-validated methods that risk potency loss. This commentary highlights the urgent need for real-world studies on insulin stability and sterility in SSA to inform evidence-based practices and improve glycemic control among diabetic patients in resource-limited settings.Keywords: diabetes, insulin stability, insulin sterility, glycemic control, Sub-Saharan Africa, SSA |
| format | Article |
| id | doaj-art-c514385761ca4b94b51cd871c886a966 |
| institution | Kabale University |
| issn | 1178-7007 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj-art-c514385761ca4b94b51cd871c886a9662025-08-24T17:31:58ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072025-08-01Volume 18Issue 130273030106082Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan AfricaKimaro E0Konje ET1Mori AT2Kidenya BR3Kaale E4Pharmaceutics and Pharmacy practice, School of Pharmacy, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, TanzaniaDepartment of Biostatistics and Epidemiology, School of Public Health, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania.Department of Global Public Health and Primary care, Section for Ethics and Health Economics, University of Bergen, NorwayDepartment of Biochemistry and Molecular biology, Catholic University of Health and Allied Sciences (CUHAS), School of Medicine, Mwanza, Tanzania.Department of Medicinal Chemistry, Muhimbili University of Health and Allied Sciences (MUHAS), School of Pharmacy, Dar es Salaam, Tanzania.Emmanuel Kimaro,1 Eveline Thobias Konje,2 Amani Thomas Mori,3 Benson Richard Kidenya,4 Eliangiringa Kaale5,6 1Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania; 2Department of Biostatistics and Epidemiology, School of Public Health, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania; 3Department of Global Public Health and Primary Care, Section for Ethics and Health Economics, University of Bergen, Bergen, Norway; 4Department of Biochemistry and Molecular Biology, Catholic University of Health and Allied Sciences (CUHAS), School of Medicine, Mwanza, Tanzania; 5Pharm R&D Laboratory, School of Pharmacy, Muhimbili University of Health and Allied Sciences (MUHAS), Dar Es Salaam, Tanzania; 6Department of Medicinal Chemistry, Muhimbili University of Health and Allied Sciences (MUHAS), School of Pharmacy, Dar Es Salaam, TanzaniaCorrespondence: Emmanuel Kimaro, Email ekimaro12@gmail.comAbstract: Insulin stability is a critical yet underexplored factor affecting diabetes outcomes in Sub-Saharan Africa (SSA). High ambient temperatures, unreliable refrigeration, and weak regulatory oversight may compromise insulin quality during storage and use. Patients often rely on traditional, non-validated methods that risk potency loss. This commentary highlights the urgent need for real-world studies on insulin stability and sterility in SSA to inform evidence-based practices and improve glycemic control among diabetic patients in resource-limited settings.Keywords: diabetes, insulin stability, insulin sterility, glycemic control, Sub-Saharan Africa, SSAhttps://www.dovepress.com/investigating-real-world-stability-and-sterility-of-in-use-insulin-an--peer-reviewed-fulltext-article-DMSODiabetesInsulin stabilityInsulin sterilityGlycemic controlSub-Saharan AfricaSSA |
| spellingShingle | Kimaro E Konje ET Mori AT Kidenya BR Kaale E Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa Diabetes, Metabolic Syndrome and Obesity Diabetes Insulin stability Insulin sterility Glycemic control Sub-Saharan Africa SSA |
| title | Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa |
| title_full | Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa |
| title_fullStr | Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa |
| title_full_unstemmed | Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa |
| title_short | Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa |
| title_sort | investigating real world stability and sterility of in use insulin an urgent public health concern in sub saharan africa |
| topic | Diabetes Insulin stability Insulin sterility Glycemic control Sub-Saharan Africa SSA |
| url | https://www.dovepress.com/investigating-real-world-stability-and-sterility-of-in-use-insulin-an--peer-reviewed-fulltext-article-DMSO |
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