Distinct distribution and responses of IgM+, IgT1+ and IgT2+ B cells in common carp

Distinct distribution and responses of IgM+, IgT1+ and IgT2+ B cells in common carp

In teleosts, the immunoglobulin classes produced by B cells are IgM, IgD, and IgT/IgZ. IgT was initially described as an immunoglobulin specialized in mucosal responses; accumulating evidence, however, shows that it is also involved in systemic immune responses. Two types of IgT/IgZ (IgT1 and IgT2)...

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Bibliographic Details
Main Authors: Awatif Eltijani, Carmen W. E. Embregts, Susana Magadan, Jingjing Wang, Sylvia Brugman, Pierre Boudinot, Geert F. Wiegertjes, Maria Forlenza
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
teleosts
IGT
IgM
mucosal B cells
systemic B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1490776/full
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