Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy

Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy

Background/Objectives: Septic cardiomyopathy (SCM) is a severe cardiac complication of sepsis, characterized by cardiac dysfunction with limited effective treatments. This study aimed to identify repurposable drugs for SCM by integrated multi-omics and network analyses. Methods: We generated a mouse...

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Bibliographic Details
Main Authors: Pei-Pei Liu, Xin-Yue Yu, Qing-Qing Pan, Jia-Jun Ren, Yu-Xuan Han, Kai Zhang, Yan Wang, Yin Huang, Tao Ban
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceuticals
Subjects:
metabolomics
transcriptomics
network medicine
acetaminophen
LC-MS
Online Access:https://www.mdpi.com/1424-8247/18/1/43
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