Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes
Background: Type 2 diabetes significantly impacts socioeconomic conditions, with periods of obesity and insulin resistance preceding diagnosis. Fasting, practiced for millennia, offers the potential to manage and possibly reverse diabetes. This study aims to assess the effects of intermittent fastin...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_758_24 |
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| author | Aparnna Unnikrishnan Nair Naveenkumar Nallathambi S Yogesh Lakshmi Murugesan Harini B. Narayanan Rajiv Ranjan Nithila Sivakumar Lakshiya Ramamoorthy K Arun |
| author_facet | Aparnna Unnikrishnan Nair Naveenkumar Nallathambi S Yogesh Lakshmi Murugesan Harini B. Narayanan Rajiv Ranjan Nithila Sivakumar Lakshiya Ramamoorthy K Arun |
| author_sort | Aparnna Unnikrishnan Nair |
| collection | DOAJ |
| description | Background:
Type 2 diabetes significantly impacts socioeconomic conditions, with periods of obesity and insulin resistance preceding diagnosis. Fasting, practiced for millennia, offers the potential to manage and possibly reverse diabetes. This study aims to assess the effects of intermittent fasting on various health indicators in obese type 2 diabetic patients.
Methodology:
Thirty obese volunteers with type 2 diabetes mellitus, uncontrolled by metformin alone, aged 20-60, were included. They followed a 16:8 intermittent fasting regimen for four weeks. Initial and postintervention measurements included height, weight, BMI, waist-hip ratio, waist circumference, fasting blood sugar, and serum insulin. Results were compared using the student t-test.
Results:
After four weeks, significant reductions were observed in anthropometric indices and fasting blood sugar, but no change in serum insulin levels.
Conclusion:
A 16:8 intermittent fasting regimen significantly reduced fasting blood glucose levels and anthropometric indices in obese type 2 diabetes patients over four weeks, with no effect on serum insulin levels. Larger and longer-term studies are needed to explore long-term effects and mechanisms. |
| format | Article |
| id | doaj-art-c4bde829e3db413da8f7e05be5174c7e |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-c4bde829e3db413da8f7e05be5174c7e2025-01-12T14:14:16ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3269S327110.4103/jpbs.jpbs_758_24Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 DiabetesAparnna Unnikrishnan NairNaveenkumar NallathambiS YogeshLakshmi MurugesanHarini B. NarayananRajiv RanjanNithila SivakumarLakshiya RamamoorthyK ArunBackground: Type 2 diabetes significantly impacts socioeconomic conditions, with periods of obesity and insulin resistance preceding diagnosis. Fasting, practiced for millennia, offers the potential to manage and possibly reverse diabetes. This study aims to assess the effects of intermittent fasting on various health indicators in obese type 2 diabetic patients. Methodology: Thirty obese volunteers with type 2 diabetes mellitus, uncontrolled by metformin alone, aged 20-60, were included. They followed a 16:8 intermittent fasting regimen for four weeks. Initial and postintervention measurements included height, weight, BMI, waist-hip ratio, waist circumference, fasting blood sugar, and serum insulin. Results were compared using the student t-test. Results: After four weeks, significant reductions were observed in anthropometric indices and fasting blood sugar, but no change in serum insulin levels. Conclusion: A 16:8 intermittent fasting regimen significantly reduced fasting blood glucose levels and anthropometric indices in obese type 2 diabetes patients over four weeks, with no effect on serum insulin levels. Larger and longer-term studies are needed to explore long-term effects and mechanisms.https://journals.lww.com/10.4103/jpbs.jpbs_758_24anthropometrydiabetes mellitushealth parametersinsulin resistanceintermittent fastingobesity |
| spellingShingle | Aparnna Unnikrishnan Nair Naveenkumar Nallathambi S Yogesh Lakshmi Murugesan Harini B. Narayanan Rajiv Ranjan Nithila Sivakumar Lakshiya Ramamoorthy K Arun Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes Journal of Pharmacy and Bioallied Sciences anthropometry diabetes mellitus health parameters insulin resistance intermittent fasting obesity |
| title | Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes |
| title_full | Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes |
| title_fullStr | Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes |
| title_full_unstemmed | Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes |
| title_short | Comprehensive Analysis of Intermittent Fasting on Anthropometric Indices, Glycemic Control, and Serum Insulin Levels in Obese Patients with Type 2 Diabetes |
| title_sort | comprehensive analysis of intermittent fasting on anthropometric indices glycemic control and serum insulin levels in obese patients with type 2 diabetes |
| topic | anthropometry diabetes mellitus health parameters insulin resistance intermittent fasting obesity |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_758_24 |
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