Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) against Rickettsia felis using integrated computational approaches

Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) against Rickettsia felis using integrated computational approaches

Rickettsia felis, responsible for flea-borne spotted fever, is a rising zoonotic pathogen posing an increasing global threat due to its expanding geographical distribution. The rise in antibiotic-resistant strains of this pathogen underscores the urgent need for new therapeutic interventions. This s...

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Bibliographic Details
Main Authors: Sudais Rahman, Hsien Liu, Mohibuallah Shah, Mashal M. Almutairi, Iram Liaqat, Tetsuya Tanaka, Chien-Chin Chen, Abdulaziz Alouffi, Abid Ali
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Veterinary Science
Subjects:
Rickettsia felis
novel drug targets
succinate dehydrogenase
in silico screening
pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1507496/full
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