Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents

Saved in:
Bibliographic Details
Main Authors: Tejaswini P. Siddappa, Akshay Ravish, Zhang Xi, Arunkumar Mohan, Swamy S. Girimanchanaika, Niranjan Pattehali Krishnamurthy, Shreeja Basappa, Santosh L. Gaonkar, Peter E. Lobie, Vijay Pandey, Basappa Basappa
Format: Article
Language:English
Published: American Chemical Society 2025-01-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.3c10504
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841536744897380352
author Tejaswini P. Siddappa
Akshay Ravish
Zhang Xi
Arunkumar Mohan
Swamy S. Girimanchanaika
Niranjan Pattehali Krishnamurthy
Shreeja Basappa
Santosh L. Gaonkar
Peter E. Lobie
Vijay Pandey
Basappa Basappa
author_facet Tejaswini P. Siddappa
Akshay Ravish
Zhang Xi
Arunkumar Mohan
Swamy S. Girimanchanaika
Niranjan Pattehali Krishnamurthy
Shreeja Basappa
Santosh L. Gaonkar
Peter E. Lobie
Vijay Pandey
Basappa Basappa
author_sort Tejaswini P. Siddappa
collection DOAJ
format Article
id doaj-art-c487238dd3f24582a0641247f20bb70b
institution Kabale University
issn 2470-1343
language English
publishDate 2025-01-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-c487238dd3f24582a0641247f20bb70b2025-01-14T11:33:58ZengAmerican Chemical SocietyACS Omega2470-13432025-01-0110111412610.1021/acsomega.3c10504Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic AgentsTejaswini P. Siddappa0Akshay Ravish1Zhang Xi2Arunkumar Mohan3Swamy S. Girimanchanaika4Niranjan Pattehali Krishnamurthy5Shreeja Basappa6Santosh L. Gaonkar7Peter E. Lobie8Vijay Pandey9Basappa Basappa10Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka, IndiaLaboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka, IndiaShenzhen Bay Laboratory, Shenzhen, ChinaLaboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka, IndiaLaboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka, IndiaNMR Research Centre, Indian Institute of Science, Bangalore, Karnataka, IndiaDepartment of Chemistry, BITS-Pilani Hyderabad Campus, Medchal, IndiaDepartment of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaShenzhen Bay Laboratory, Shenzhen, ChinaInstitute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, ChinaLaboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka, Indiahttps://doi.org/10.1021/acsomega.3c10504
spellingShingle Tejaswini P. Siddappa
Akshay Ravish
Zhang Xi
Arunkumar Mohan
Swamy S. Girimanchanaika
Niranjan Pattehali Krishnamurthy
Shreeja Basappa
Santosh L. Gaonkar
Peter E. Lobie
Vijay Pandey
Basappa Basappa
Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
ACS Omega
title Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
title_full Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
title_fullStr Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
title_full_unstemmed Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
title_short Discovery of 2‑Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents
title_sort discovery of 2 pyrazolines that inhibit the phosphorylation of stat3 as nanomolar cytotoxic agents
url https://doi.org/10.1021/acsomega.3c10504
work_keys_str_mv AT tejaswinipsiddappa discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT akshayravish discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT zhangxi discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT arunkumarmohan discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT swamysgirimanchanaika discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT niranjanpattehalikrishnamurthy discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT shreejabasappa discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT santoshlgaonkar discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT peterelobie discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT vijaypandey discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents
AT basappabasappa discoveryof2pyrazolinesthatinhibitthephosphorylationofstat3asnanomolarcytotoxicagents