Change detection in the dynamics of an intracellular protein synthesis model using nonlinear Kalman filtering
A method for early diagnosis of parametric changes in intracellular protein synthesis models (e.g. the p53 protein - mdm2 inhibitor model) is developed with the use of a nonlinear Kalman Filtering approach (Derivative-free nonlinear Kalman Filter) and of statistical change detection methods. The int...
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Main Authors: | Gerasimos G. Rigatos, Efthymia G. Rigatou, Jean Daniel Djida |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-05-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1017 |
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