Predictive value of machine learning model based on CT values for urinary tract infection stones

Summary: Preoperative diagnosis of infection stones presents a significant clinical challenge. We developed a machine learning model to predict urinary infection stones using computed tomography (CT) values, enabling in vivo preoperative identification. In this study, we included 1209 patients who u...

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Main Authors: Jiaxin Li, Yao Du, Gaoming Huang, Chiyu Zhang, Zhenfeng Ye, Jinghui Zhong, Xiaoqing Xi, Yawei Huang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224020686
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author Jiaxin Li
Yao Du
Gaoming Huang
Chiyu Zhang
Zhenfeng Ye
Jinghui Zhong
Xiaoqing Xi
Yawei Huang
author_facet Jiaxin Li
Yao Du
Gaoming Huang
Chiyu Zhang
Zhenfeng Ye
Jinghui Zhong
Xiaoqing Xi
Yawei Huang
author_sort Jiaxin Li
collection DOAJ
description Summary: Preoperative diagnosis of infection stones presents a significant clinical challenge. We developed a machine learning model to predict urinary infection stones using computed tomography (CT) values, enabling in vivo preoperative identification. In this study, we included 1209 patients who underwent urinary lithotripsy at our hospital. Seven machine learning algorithms along with eleven preoperative variables were used to construct the prediction model. Subsequently, model performance was evaluated by calculating AUC and AUPR for subjects in the validation set. On the validation set, all seven machine learning models demonstrated strong discrimination (AUC: 0.687–0.947). Additionally, the XGBoost model was identified as the optimal model significantly outperforming the traditional LR model. Taken together, the XGBoost model is the first machine learning model for preoperative prediction of infection stones based on CT values. It can rapidly and accurately identify infection stones in vitro, providing valuable guidance for urologists in managing these stones.
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institution Kabale University
issn 2589-0042
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publishDate 2024-12-01
publisher Elsevier
record_format Article
series iScience
spelling doaj-art-c3d4dca0b23a4cc6b55143fdfa888a2d2024-12-22T05:28:39ZengElsevieriScience2589-00422024-12-012712110843Predictive value of machine learning model based on CT values for urinary tract infection stonesJiaxin Li0Yao Du1Gaoming Huang2Chiyu Zhang3Zhenfeng Ye4Jinghui Zhong5Xiaoqing Xi6Yawei Huang7Department of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaDepartment of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaDepartment of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaDepartment of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaDepartment of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaDepartment of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, ChinaDepartment of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Corresponding authorDepartment of Urology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Corresponding authorSummary: Preoperative diagnosis of infection stones presents a significant clinical challenge. We developed a machine learning model to predict urinary infection stones using computed tomography (CT) values, enabling in vivo preoperative identification. In this study, we included 1209 patients who underwent urinary lithotripsy at our hospital. Seven machine learning algorithms along with eleven preoperative variables were used to construct the prediction model. Subsequently, model performance was evaluated by calculating AUC and AUPR for subjects in the validation set. On the validation set, all seven machine learning models demonstrated strong discrimination (AUC: 0.687–0.947). Additionally, the XGBoost model was identified as the optimal model significantly outperforming the traditional LR model. Taken together, the XGBoost model is the first machine learning model for preoperative prediction of infection stones based on CT values. It can rapidly and accurately identify infection stones in vitro, providing valuable guidance for urologists in managing these stones.http://www.sciencedirect.com/science/article/pii/S2589004224020686NephrologyBioinformatics
spellingShingle Jiaxin Li
Yao Du
Gaoming Huang
Chiyu Zhang
Zhenfeng Ye
Jinghui Zhong
Xiaoqing Xi
Yawei Huang
Predictive value of machine learning model based on CT values for urinary tract infection stones
iScience
Nephrology
Bioinformatics
title Predictive value of machine learning model based on CT values for urinary tract infection stones
title_full Predictive value of machine learning model based on CT values for urinary tract infection stones
title_fullStr Predictive value of machine learning model based on CT values for urinary tract infection stones
title_full_unstemmed Predictive value of machine learning model based on CT values for urinary tract infection stones
title_short Predictive value of machine learning model based on CT values for urinary tract infection stones
title_sort predictive value of machine learning model based on ct values for urinary tract infection stones
topic Nephrology
Bioinformatics
url http://www.sciencedirect.com/science/article/pii/S2589004224020686
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