Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective

Objectives: To investigate the midterm results after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. Methods: Between October 2014 and April 2021, 196 patients underwent zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. The true lum...

Full description

Saved in:
Bibliographic Details
Main Authors: Takuya Wada, MD, Hiroshi Yamamoto, MD, PhD, Daichi Takagi, MD, PhD, Takayuki Kadohama, MD, PhD, Gembu Yamaura, MD, PhD, Kentaro Kiryu, MD, PhD, Itaru Igarashi, MD
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:JTCVS Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666250722003431
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849237512369733632
author Takuya Wada, MD
Hiroshi Yamamoto, MD, PhD
Daichi Takagi, MD, PhD
Takayuki Kadohama, MD, PhD
Gembu Yamaura, MD, PhD
Kentaro Kiryu, MD, PhD
Itaru Igarashi, MD
author_facet Takuya Wada, MD
Hiroshi Yamamoto, MD, PhD
Daichi Takagi, MD, PhD
Takayuki Kadohama, MD, PhD
Gembu Yamaura, MD, PhD
Kentaro Kiryu, MD, PhD
Itaru Igarashi, MD
author_sort Takuya Wada, MD
collection DOAJ
description Objectives: To investigate the midterm results after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. Methods: Between October 2014 and April 2021, 196 patients underwent zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. The true lumen area, aortic lumen area, and false lumen status were assessed at four aortic levels, the proximal and distal descending thoracic aorta (level A and level B, respectively), celiac artery branching (level C), and terminal aorta (level D). Aortic remodeling (postoperative area as a percentage of the preoperative area) was classified into 3 groups, positive (true lumen area ≥120% with aortic lumen <120% or true lumen area ≥80% with aortic lumen <80%), minimal (80% ≤ true lumen area and aortic lumen area <120%), and negative remodeling (all other changes). Results: In-hospital mortality was 13 (6.6%) patients. The overall survival rate was 85.1% at 5 years. The freedom from distal aortic reintervention was 89.9% at 5 years. The prevalence of completely thrombosed or obliterated false lumen at 2 years was 96.8% at level A, 88.4% at level B, 47.2% at level C, and 27.6% at level D. The prevalence of positive aortic remodeling at 2 years was 84.7% at level A, 75.0% at level B, 29.2% at level C, and 16.7% at level D. Conclusions: Zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection can avoid invasive aortic arch resection and facilitate aortic remodeling of the descending thoracic aorta. The FET effect on aortic remodeling is limited at the aortic level below the FET stent end.
format Article
id doaj-art-c3cc52c626104c9f90f52f6d991027b8
institution Kabale University
issn 2666-2507
language English
publishDate 2022-08-01
publisher Elsevier
record_format Article
series JTCVS Techniques
spelling doaj-art-c3cc52c626104c9f90f52f6d991027b82025-08-20T04:01:57ZengElsevierJTCVS Techniques2666-25072022-08-0114293810.1016/j.xjtc.2022.05.013Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspectiveTakuya Wada, MD0Hiroshi Yamamoto, MD, PhD1Daichi Takagi, MD, PhD2Takayuki Kadohama, MD, PhD3Gembu Yamaura, MD, PhD4Kentaro Kiryu, MD, PhD5Itaru Igarashi, MD6Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanAddress for reprints: Hiroshi Yamamoto, MD, PhD, Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Hondo 1-1-1, Akita, Akita 010-8543, Japan.; Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanDepartment of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanDepartment of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanDepartment of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanDepartment of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanDepartment of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, JapanObjectives: To investigate the midterm results after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. Methods: Between October 2014 and April 2021, 196 patients underwent zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection. The true lumen area, aortic lumen area, and false lumen status were assessed at four aortic levels, the proximal and distal descending thoracic aorta (level A and level B, respectively), celiac artery branching (level C), and terminal aorta (level D). Aortic remodeling (postoperative area as a percentage of the preoperative area) was classified into 3 groups, positive (true lumen area ≥120% with aortic lumen <120% or true lumen area ≥80% with aortic lumen <80%), minimal (80% ≤ true lumen area and aortic lumen area <120%), and negative remodeling (all other changes). Results: In-hospital mortality was 13 (6.6%) patients. The overall survival rate was 85.1% at 5 years. The freedom from distal aortic reintervention was 89.9% at 5 years. The prevalence of completely thrombosed or obliterated false lumen at 2 years was 96.8% at level A, 88.4% at level B, 47.2% at level C, and 27.6% at level D. The prevalence of positive aortic remodeling at 2 years was 84.7% at level A, 75.0% at level B, 29.2% at level C, and 16.7% at level D. Conclusions: Zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection can avoid invasive aortic arch resection and facilitate aortic remodeling of the descending thoracic aorta. The FET effect on aortic remodeling is limited at the aortic level below the FET stent end.http://www.sciencedirect.com/science/article/pii/S2666250722003431acute type A aortic dissectionzone 0 arch repairfrozen elephant trunkaortic remodelingdistal stent-induced new entry
spellingShingle Takuya Wada, MD
Hiroshi Yamamoto, MD, PhD
Daichi Takagi, MD, PhD
Takayuki Kadohama, MD, PhD
Gembu Yamaura, MD, PhD
Kentaro Kiryu, MD, PhD
Itaru Igarashi, MD
Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
JTCVS Techniques
acute type A aortic dissection
zone 0 arch repair
frozen elephant trunk
aortic remodeling
distal stent-induced new entry
title Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
title_full Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
title_fullStr Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
title_full_unstemmed Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
title_short Aortic remodeling, reintervention, and survival after zone 0 arch repair with frozen elephant trunks for acute type A aortic dissection: Midterm resultsCentral MessagePerspective
title_sort aortic remodeling reintervention and survival after zone 0 arch repair with frozen elephant trunks for acute type a aortic dissection midterm resultscentral messageperspective
topic acute type A aortic dissection
zone 0 arch repair
frozen elephant trunk
aortic remodeling
distal stent-induced new entry
url http://www.sciencedirect.com/science/article/pii/S2666250722003431
work_keys_str_mv AT takuyawadamd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT hiroshiyamamotomdphd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT daichitakagimdphd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT takayukikadohamamdphd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT gembuyamauramdphd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT kentarokiryumdphd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective
AT itaruigarashimd aorticremodelingreinterventionandsurvivalafterzone0archrepairwithfrozenelephanttrunksforacutetypeaaorticdissectionmidtermresultscentralmessageperspective