Enhanced chemotherapy response in hepatocellular carcinoma: synergistic effects of miR-122 and doxorubicin co-delivery system inducing apoptosis and DNA damage

Enhanced chemotherapy response in hepatocellular carcinoma: synergistic effects of miR-122 and doxorubicin co-delivery system inducing apoptosis and DNA damage

Abstract Background Cancer cells can resist chemotherapy through various mechanisms, diminishing treatment outcomes. Research had indicated that combining miR-122 with doxorubicin (DOX) can improve hepatocellular carcinoma (HCC) therapy. Results To explore this, we created a one-pot co-delivery syst...

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Bibliographic Details
Main Authors: Xiuyun Lin, Jie Liu, Guangfeng Wu, Xiu Yang, Wenqiang Yan, Nanfeng Fan, Hui Li
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Cancer Nanotechnology
Subjects:
Chemotherapy resistance
miR-122
Hepatocellular carcinoma (HCC)
Nanoparticles
Apoptosis
Online Access:https://doi.org/10.1186/s12645-024-00287-x
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