Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures
Background Hip fractures are frequent injuries in older patients and are associated with high mortality rates. This study assessed the association between serum lactate level and 30-day mortality in older patients with unilateral hip fractures and examined the prognostic value of this association on...
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Korea Geriatrics Society
2024-09-01
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| Series: | Annals of Geriatric Medicine and Research |
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| Online Access: | http://www.e-agmr.org/upload/pdf/agmr-24-0011.pdf |
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| author | Handan Özen Olcay Emine Emektar Zeynep Saral Öztürk Sedat Akkan Yunsur Çevik |
| author_facet | Handan Özen Olcay Emine Emektar Zeynep Saral Öztürk Sedat Akkan Yunsur Çevik |
| author_sort | Handan Özen Olcay |
| collection | DOAJ |
| description | Background Hip fractures are frequent injuries in older patients and are associated with high mortality rates. This study assessed the association between serum lactate level and 30-day mortality in older patients with unilateral hip fractures and examined the prognostic value of this association on the clinical outcomes of these patients. Methods This retrospective, single-center study included patients aged ≥65 years admitted to the emergency department due to low-energy trauma and diagnosed with unilateral hip fracture upon admission. The additional inclusion criteria were patients with independent ambulation or walker or cane assistance before the injury, with available data on serum lactate levels on venous blood gas analysis, and who underwent surgery. Results Among the 330 included patients, 30.9% experienced postoperative complications and 10.3% died within 30 days. Using a lactate cut-off value of 2 mmol/L to distinguish between living and deceased patients, the sensitivity and specificity were 41% and 88%, respectively. Multivariate logistic regression analysis revealed that high lactate and low albumin levels and male sex were associated with mortality. Conclusion Identifying risk factors for mortality in geriatric patients with hip fractures is important. Male sex, low albumin levels, and particularly increased lactate levels were independent predictors of short-term mortality in these patients. |
| format | Article |
| id | doaj-art-c3b386681eb04893aafd38d3d5b32e73 |
| institution | Kabale University |
| issn | 2508-4798 2508-4909 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Korea Geriatrics Society |
| record_format | Article |
| series | Annals of Geriatric Medicine and Research |
| spelling | doaj-art-c3b386681eb04893aafd38d3d5b32e732024-11-19T00:12:41ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092024-09-0128330130610.4235/agmr.24.00111145Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip FracturesHandan Özen Olcay0Emine Emektar1Zeynep Saral Öztürk2Sedat Akkan3Yunsur Çevik4 Department of Emergency Medicine, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Türkiye Department of Emergency Medicine, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Türkiye Department of Emergency Medicine, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Türkiye Department of Emergency Medicine, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Türkiye Department of Emergency Medicine, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, TürkiyeBackground Hip fractures are frequent injuries in older patients and are associated with high mortality rates. This study assessed the association between serum lactate level and 30-day mortality in older patients with unilateral hip fractures and examined the prognostic value of this association on the clinical outcomes of these patients. Methods This retrospective, single-center study included patients aged ≥65 years admitted to the emergency department due to low-energy trauma and diagnosed with unilateral hip fracture upon admission. The additional inclusion criteria were patients with independent ambulation or walker or cane assistance before the injury, with available data on serum lactate levels on venous blood gas analysis, and who underwent surgery. Results Among the 330 included patients, 30.9% experienced postoperative complications and 10.3% died within 30 days. Using a lactate cut-off value of 2 mmol/L to distinguish between living and deceased patients, the sensitivity and specificity were 41% and 88%, respectively. Multivariate logistic regression analysis revealed that high lactate and low albumin levels and male sex were associated with mortality. Conclusion Identifying risk factors for mortality in geriatric patients with hip fractures is important. Male sex, low albumin levels, and particularly increased lactate levels were independent predictors of short-term mortality in these patients.http://www.e-agmr.org/upload/pdf/agmr-24-0011.pdfhip fracturesemergency departmentelderlylactate concentration30-day mortality |
| spellingShingle | Handan Özen Olcay Emine Emektar Zeynep Saral Öztürk Sedat Akkan Yunsur Çevik Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures Annals of Geriatric Medicine and Research hip fractures emergency department elderly lactate concentration 30-day mortality |
| title | Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures |
| title_full | Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures |
| title_fullStr | Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures |
| title_full_unstemmed | Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures |
| title_short | Association of Serum Lactate Levels Measured in the Emergency Department with 30-Day Mortality in Older Patients with Unilateral Hip Fractures |
| title_sort | association of serum lactate levels measured in the emergency department with 30 day mortality in older patients with unilateral hip fractures |
| topic | hip fractures emergency department elderly lactate concentration 30-day mortality |
| url | http://www.e-agmr.org/upload/pdf/agmr-24-0011.pdf |
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