Adhesive polyelectrolyte coating through UV-triggered polymerization on PLGA particles for enhanced drug delivery to inflammatory intestinal mucosa

Adhesive polyelectrolyte coating through UV-triggered polymerization on PLGA particles for enhanced drug delivery to inflammatory intestinal mucosa

Abstract Administering medication precisely to the inflamed intestinal sites to treat ulcerative colitis (UC), with minimized side effects, is of urgent need. In UC, the inflammation damaged mucosa contains a large number of amino groups which are positively charged, providing new opportunities for...

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Bibliographic Details
Main Authors:	Jie Zhang, Yi-jing Yin, Xing-wang Wang, Wei-qi Lu, Zhao-yang Chen, Chao-hui Yu, Ke-feng Ren, Cheng-fu Xu
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Series:	Journal of Nanobiotechnology
Subjects:	Ulcerative colitis Adhesive coating UV-triggered polymerization PLGA particles Drug delivery
Online Access:	https://doi.org/10.1186/s12951-024-03066-3
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