Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis

Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis

ABSTRACT Chlamydia is an obligate intracellular bacterium that undergoes a complex biphasic developmental cycle, alternating between the smaller, infectious, non-dividing elementary body (EB) and the larger, non-infectious but dividing reticulate body. Due to the differences between these functional...

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Bibliographic Details
Main Authors: Aaron A. Jensen, Saba Firdous, Lei Lei, Derek J. Fisher, Scot P. Ouellette
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
Chlamydia
ClpC
ClpP
AAA+ ATPase
Clp protease
differentiation
Online Access:https://journals.asm.org/doi/10.1128/mbio.02870-24
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