Bayesian polygenic risk estimation approach to nuclear families with discordant sib-pairs for myelomeningocele.

Bayesian polygenic risk estimation approach to nuclear families with discordant sib-pairs for myelomeningocele.

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Myelomeningocele (MMC) is the most severe and disabling form of spina bifida with chronic health multisystem complications and social and economic family and health systems burden. In the present study, we aimed to investigate the genetic risk estimate for MMC in a cohort of 203 Mexican nuclear fami...

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Bibliographic Details
Main Authors: Adolfo Aguayo-Gómez, Leonora Luna-Muñoz, Yevgeniya Svyryd, Luis Ángel Muñoz-Téllez, Osvaldo M Mutchinick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316378
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