Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice
Conclusions: Our results suggest that Ces1f plays a hepatoprotective role through regulating KC polarization, which might contribute to anti-inflammatory and antioxidative effects in LPS/D-Gal-induced ALF mice.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/cjgh/6410484 |
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| _version_ | 1846101724249456640 |
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| author | Sai Zhao Xue Yang Yu He Qian Yu Liang-Ming Liu |
| author_facet | Sai Zhao Xue Yang Yu He Qian Yu Liang-Ming Liu |
| author_sort | Sai Zhao |
| collection | DOAJ |
| description | Conclusions: Our results suggest that Ces1f plays a hepatoprotective role through regulating KC polarization, which might contribute to anti-inflammatory and antioxidative effects in LPS/D-Gal-induced ALF mice. |
| format | Article |
| id | doaj-art-c32d58f128c64f91b7f31289d914a809 |
| institution | Kabale University |
| issn | 2291-2797 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-c32d58f128c64f91b7f31289d914a8092024-12-29T00:00:02ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27972024-01-01202410.1155/cjgh/6410484Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in MiceSai Zhao0Xue Yang1Yu He2Qian Yu3Liang-Ming Liu4Department of Infectious DiseasesDepartment of Infectious DiseasesDepartment of Infectious DiseasesDepartment of Infectious DiseasesDepartment of Infectious DiseasesConclusions: Our results suggest that Ces1f plays a hepatoprotective role through regulating KC polarization, which might contribute to anti-inflammatory and antioxidative effects in LPS/D-Gal-induced ALF mice.http://dx.doi.org/10.1155/cjgh/6410484 |
| spellingShingle | Sai Zhao Xue Yang Yu He Qian Yu Liang-Ming Liu Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice Canadian Journal of Gastroenterology and Hepatology |
| title | Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice |
| title_full | Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice |
| title_fullStr | Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice |
| title_full_unstemmed | Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice |
| title_short | Kupffer-Cell-Targeted Carboxylesterase 1f Knockdown Deteriorates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Regulating Cellular Polarization in Mice |
| title_sort | kupffer cell targeted carboxylesterase 1f knockdown deteriorates lipopolysaccharide d galactosamine induced acute liver failure through regulating cellular polarization in mice |
| url | http://dx.doi.org/10.1155/cjgh/6410484 |
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