‘Gel-Stacks’ gently confine or reversibly immobilize arrays of single DNA molecules for manipulation and study
Large DNA molecules (>20 kb) are difficult analytes prone to breakage during serial manipulations and cannot be ‘rescued’ as full-length amplicons. Accordingly, to present, modify and analyze arrays of large, single DNA molecules, we created an easily realizable approach offering gentle confineme...
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Main Authors: | Susana Calle-Casteñeda, Eamon Winden, Alejandro Vasquez-Echeverri, Matthew Schickling, Evelyn Browning, Juan Pablo Hernandez Ortiz, David C Schwartz |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-06-01
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Series: | BioTechniques |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.2144/btn-2023-0123 |
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