BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice
Abstract Background While more and more people tend to use herbal products thinking they are safer than conventional western medicine, the reality is other. If natural products are bio-active and possess potential therapeutic activities, then the benefit/risk balance should be considered like any ot...
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| Format: | Article |
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BMC
2024-12-01
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| Series: | BMC Complementary Medicine and Therapies |
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| Online Access: | https://doi.org/10.1186/s12906-024-04706-9 |
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| author | Anthony Cnudde Camille Allely Natacha Biset Pierre Champy Nathalie Fouilhé Fanny Huret Sibi Lawson Aline Mercan Doris Pascale Noukela Noumi Serge Michalet Andrea Montis Stephanie Pochet Audrey Schils Cecilia Tangeten Michel Tod Pierre Van Antwerpen Audrey Vervacke Florence Souard |
| author_facet | Anthony Cnudde Camille Allely Natacha Biset Pierre Champy Nathalie Fouilhé Fanny Huret Sibi Lawson Aline Mercan Doris Pascale Noukela Noumi Serge Michalet Andrea Montis Stephanie Pochet Audrey Schils Cecilia Tangeten Michel Tod Pierre Van Antwerpen Audrey Vervacke Florence Souard |
| author_sort | Anthony Cnudde |
| collection | DOAJ |
| description | Abstract Background While more and more people tend to use herbal products thinking they are safer than conventional western medicine, the reality is other. If natural products are bio-active and possess potential therapeutic activities, then the benefit/risk balance should be considered like any other health product. Some herbs are known to have the potential to interact with patient’s treatment and to cause adverse drug reactions. While these are scarce, they are potentially harmful, and can lead to major sequels and even death in some cases. Despite these known facts, little guidelines about how to evaluate the risk of interaction and to handle them exist in literature. Notably, few scales allowing to assess the risk of a specific combination of herbs and drugs exist. Method We propose a new scoring method BABINE (Boosting Analysis of Bibliography for herb- drug INteraction Evaluation) and discuss a scale to evaluate this risk based on iterative rounds of experts’ discussion. Results After 6 rounds of case reports/clinical studies evaluation, we analyzed and synthesized criteria identified as important by the experts and developed a corresponding evaluation scale. Conclusion Even if our scale greatly simplifies pharmacological events, we believe it provides a robust and transparent way to rapidly assess the risk of adverse event. |
| format | Article |
| id | doaj-art-c2e7ed1061b245e78162989bb5f45aa5 |
| institution | Kabale University |
| issn | 2662-7671 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary Medicine and Therapies |
| spelling | doaj-art-c2e7ed1061b245e78162989bb5f45aa52024-12-22T12:14:54ZengBMCBMC Complementary Medicine and Therapies2662-76712024-12-0124111110.1186/s12906-024-04706-9BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practiceAnthony Cnudde0Camille Allely1Natacha Biset2Pierre Champy3Nathalie Fouilhé4Fanny Huret5Sibi Lawson6Aline Mercan7Doris Pascale Noukela Noumi8Serge Michalet9Andrea Montis10Stephanie Pochet11Audrey Schils12Cecilia Tangeten13Michel Tod14Pierre Van Antwerpen15Audrey Vervacke16Florence Souard17Department of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB)CNHIMDepartment of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB)Équipe Chimie des Substances Naturelles, BioCIS, CNRS, Université Paris-SaclayCentre Hospitalier Universitaire Grenoble AlpesNutrition Risk Assessment Unit, French Agency for Food, Environmental and Occupational, Health & Safety (ANSES)Université Libre de BruxellesHospices Civils de Lyon, and LBBE, Hôpital de la Croix-Rousse, Université Claude Bernard Lyon 1Université Libre de BruxellesPharmacognosy, Department of Drug Sciences, Institut des Sciences Pharmaceutiques et Biologiques (ISPB), UMR 5557 Ecologie Microbienne, Université Claude Bernard Lyon 1RD3 Unit of Pharmacognosy, Bioanalysis and Drug Discovery, Faculty of Pharmacy, Université Libre de BruxellesDepartment of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB)Department of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB)RD3 Unit of Pharmacognosy, Bioanalysis and Drug Discovery, Faculty of Pharmacy, Université Libre de BruxellesHospices Civils de Lyon, and LBBE, Hôpital de la Croix-Rousse, Université Claude Bernard Lyon 1RD3 Unit of Pharmacognosy, Bioanalysis and Drug Discovery, Faculty of Pharmacy, Université Libre de BruxellesHôpital universitaire de Bruxelles - site Erasme (HUB) BEDepartment of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB)Abstract Background While more and more people tend to use herbal products thinking they are safer than conventional western medicine, the reality is other. If natural products are bio-active and possess potential therapeutic activities, then the benefit/risk balance should be considered like any other health product. Some herbs are known to have the potential to interact with patient’s treatment and to cause adverse drug reactions. While these are scarce, they are potentially harmful, and can lead to major sequels and even death in some cases. Despite these known facts, little guidelines about how to evaluate the risk of interaction and to handle them exist in literature. Notably, few scales allowing to assess the risk of a specific combination of herbs and drugs exist. Method We propose a new scoring method BABINE (Boosting Analysis of Bibliography for herb- drug INteraction Evaluation) and discuss a scale to evaluate this risk based on iterative rounds of experts’ discussion. Results After 6 rounds of case reports/clinical studies evaluation, we analyzed and synthesized criteria identified as important by the experts and developed a corresponding evaluation scale. Conclusion Even if our scale greatly simplifies pharmacological events, we believe it provides a robust and transparent way to rapidly assess the risk of adverse event.https://doi.org/10.1186/s12906-024-04706-9Her-drug interactionsRiskPhytovigilancePharmacovigilanceDelphiDecision support |
| spellingShingle | Anthony Cnudde Camille Allely Natacha Biset Pierre Champy Nathalie Fouilhé Fanny Huret Sibi Lawson Aline Mercan Doris Pascale Noukela Noumi Serge Michalet Andrea Montis Stephanie Pochet Audrey Schils Cecilia Tangeten Michel Tod Pierre Van Antwerpen Audrey Vervacke Florence Souard BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice BMC Complementary Medicine and Therapies Her-drug interactions Risk Phytovigilance Pharmacovigilance Delphi Decision support |
| title | BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice |
| title_full | BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice |
| title_fullStr | BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice |
| title_full_unstemmed | BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice |
| title_short | BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice |
| title_sort | babine an original and user friendly scale for the simple and quick management of herb drug interactions in clinical practice |
| topic | Her-drug interactions Risk Phytovigilance Pharmacovigilance Delphi Decision support |
| url | https://doi.org/10.1186/s12906-024-04706-9 |
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