The MVA-VP2-NS1-2A-NS2-Nt vaccine candidate provides heterologous protection in sheep against bluetongue virus

The MVA-VP2-NS1-2A-NS2-Nt vaccine candidate provides heterologous protection in sheep against bluetongue virus

Bluetongue (BT) is an important arthropod-borne livestock disease transmitted by Culicoides midges. The etiological agent, Bluetongue virus (BTV), can lead to severe economic losses due to reduced productivity and trade restrictions. Nowadays, classical vaccines based on inactivated viruses are used...

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Bibliographic Details
Main Authors: Luis Jiménez-Cabello, Sergio Utrilla-Trigo, Miguel Illescas-Amo, Karen Rodríguez-Sabando, Julio Benavides-Silván, Eva Calvo-Pinilla, Javier Ortego
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
bluetongue virus (BTV)
orbivirus
vaccine
MVA
DIVA
multiserotype
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1566225/full
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