Structural pre-training improves physical accuracy of antibody structure prediction using deep learning.
Protein folding problem obtained a practical solution recently, owing to advances in deep learning. There are classes of proteins though, such as antibodies, that are structurally unique, where the general solution still lacks. In particular, the prediction of the CDR-H3 loop, which is an instrument...
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| Main Authors: | Jarosław Kończak, Bartosz Janusz, Jakub Młokosiewicz, Tadeusz Satława, Sonia Wróbel, Paweł Dudzic, Konrad Krawczyk |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
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| Series: | ImmunoInformatics |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667119023000083 |
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