Structural pre-training improves physical accuracy of antibody structure prediction using deep learning.

Protein folding problem obtained a practical solution recently, owing to advances in deep learning. There are classes of proteins though, such as antibodies, that are structurally unique, where the general solution still lacks. In particular, the prediction of the CDR-H3 loop, which is an instrument...

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Bibliographic Details
Main Authors: Jarosław Kończak, Bartosz Janusz, Jakub Młokosiewicz, Tadeusz Satława, Sonia Wróbel, Paweł Dudzic, Konrad Krawczyk
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:ImmunoInformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119023000083
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