Durable complete response after combined treatment with tumor-infiltrating lymphocytes and oncolytic adenovirus (TILT-123) in a patient with metastatic mucosal melanoma

Durable complete response after combined treatment with tumor-infiltrating lymphocytes and oncolytic adenovirus (TILT-123) in a patient with metastatic mucosal melanoma

Background: Despite significant advancements in the treatment of malignant melanoma, metastatic mucosal melanoma remains a therapeutic challenge due to its complex pathogenesis, distinct pathological characteristics, and limited response to immunotherapy. Combining different immunotherapeutic approa...

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Main Authors: T.J. Monberg, T. Kudling, B. Albieri, S. Pakola, E. Ellebaek, M. Donia, R.L. Eefsen, C. von Buchwald, C. Kistler, J.M. Santos, J. Clubb, L. Haybout, M.C.W. Westergaard, D.C.A. Quixabeira, E. Jirovec, R. Havunen, S. Sorsa, V. Cervera-Carrascon, A. Hemminki, I.M. Svane
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Immuno-Oncology and Technology
Subjects:
case report
mucosal melanoma
tumor-infiltrating lymphocytes
oncolytic virus therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018824000236
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