Down-regulation of ATM/hnRNPK signaling reduces adriamycin resistance of myeloid leukemia

Down-regulation of ATM/hnRNPK signaling reduces adriamycin resistance of myeloid leukemia

Objective To explore the role of ATM/hnRNPK signaling in the adriamycin resistance of acute myeloid leukemia. Methods Expression of ATM was examined in the adriamycin resistant and sensitive leukemia cell strains with Western blot. ATM expression was down-regulated by RNAi and ATM inhibitor in the...

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Bibliographic Details
Main Author: ZHANG Jinfang, ZHONG Mingyan, YANG Quan, FENG Bei, LI Xingdong
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-12-01
Series:Jichu yixue yu linchuang
Subjects:
atm/hnrnpk|autophagy|leukemia|adriamycin|drug resistance
Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-12-1638.pdf
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