Short-Term Oral Administration of 1.5 μg/kg bw/day of Deoxynivalenol Significantly Exacerbates Inflammatory and Itching Symptoms in a Mouse Model of Imiquimod-Induced Psoriasis

Short-Term Oral Administration of 1.5 μg/kg bw/day of Deoxynivalenol Significantly Exacerbates Inflammatory and Itching Symptoms in a Mouse Model of Imiquimod-Induced Psoriasis

Deoxynivalenol (DON) is a mycotoxin commonly found worldwide and is implicated in various health effects. We recently demonstrated that subacute oral exposure to DON significantly exacerbates symptoms of type 2 helper T-cell-mediated allergic diseases in a model. We aim to investigate the role of or...

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Bibliographic Details
Main Authors: Takayoshi Miyamoto, Mariko Komuro, Ryota Aihara, Chiharu Ohira, Mao Kaneki, Naoki Iwashita, Yoshiichi Takagi, Atsushi Miyasaka, Masayo Kushiro, Shiro Miyake, Tomoki Fukuyama
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Toxins
Subjects:
deoxynivalenol
mycotoxin
psoriasis
IL-17
TNF-α
Online Access:https://www.mdpi.com/2072-6651/17/2/47
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