Reproductive integration of leptin and kisspeptin in small ruminants: Mechanisms, biomarker potential, and prospects for precision breeding

Reproductive integration of leptin and kisspeptin in small ruminants: Mechanisms, biomarker potential, and prospects for precision breeding

Background and Aim: Kisspeptin and leptin (LEP) are two essential proteins that play a central role in regulating reproductive hormones in small ruminants through the hypothalamic-pituitary-gonadal axis. These proteins influence the secretion of gonadotropin-releasing hormone, which, in turn, contro...

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Bibliographic Details
Main Authors: Herdis Herdis, Ismeth Inounu, Santoso Santoso, Rahma Isartina Anwar, Sari Yanti Hayanti, Mohammad Firdaus Hudaya, Desiana Ade Mahari, Florentina Bety Indah Lupitasari, Anita Hafid, Marchie Asrid da Costa, Nur Adianto, Pradita Iustitia Sitaresmi
Format: Article
Language:English
Published: Veterinary World 2025-06-01
Series:Veterinary World
Subjects:
body condition score
estrous regulation
gene polymorphism
gonadotropin-releasing hormone regulation
hypothalamic-pituitary-gonadal axis
kisspeptin
leptin
livestock reproduction
metabolic-reproductive interaction
puberty induction
fertility markers
reproductive biomarkers
selection traits
small ruminants
therapeutic targets
Online Access:https://www.veterinaryworld.org/Vol.18/June-2025/20.pdf
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