Elevated neutrophil-to-lymphocyte ratios correlate with increased clozapine concentration-to-dose ratios during titration

Elevated neutrophil-to-lymphocyte ratios correlate with increased clozapine concentration-to-dose ratios during titration

Abstract Few cohort studies have examined the relationship between inflammation and increased clozapine blood levels. The purpose of this study was to investigate the relationship between the neutrophil-to-lymphocyte ratio (NLR), a marker of inflammation, and the clozapine concentration-to-dose (C/D...

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Bibliographic Details
Main Authors: Bunichiro Onodera, Mutsumi Sakata, Kazuro Ikawa, Daisuke Kume, Naoki Horikawa, Hiroshi Komatsu, Takuhiro Yamaguchi, Hiroaki Tomita, Yuki Kikuchi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-025-00648-4
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