An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis
Abstract Magnetic compression anastomosis (MCA) for esophageal stenosis requires the insertion of magnets through two channels, transoral and transgastrostomy. Herein, we designed a Y-Z deformable self-assembled magnetic anastomosis ring (Y-Z DSAMAR) for esophageal stricture anastomosis through the...
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Nature Portfolio
2024-12-01
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| Online Access: | https://doi.org/10.1038/s41598-024-81856-3 |
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| author | Miaomiao Zhang Xuhe Zhao Qiuye Zhong Linxin Shen Ruimin Gong Yi Lyu Xiaopeng Yan |
| author_facet | Miaomiao Zhang Xuhe Zhao Qiuye Zhong Linxin Shen Ruimin Gong Yi Lyu Xiaopeng Yan |
| author_sort | Miaomiao Zhang |
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| description | Abstract Magnetic compression anastomosis (MCA) for esophageal stenosis requires the insertion of magnets through two channels, transoral and transgastrostomy. Herein, we designed a Y-Z deformable self-assembled magnetic anastomosis ring (Y-Z DSAMAR) for esophageal stricture anastomosis through the transoral passage only. We introduce a Y-Z DSAMAR and verify its feasibility for single-access esophageal stenosis anastomosis in isolated organs. We procured esophagi from 10 pigs. Next, we ligated the middle part of these esophagi with 7 − 0 silk to prepare an esophageal stenosis model. The linear Y-Z DSAMAR completed the deformation self-assembly and transitioned from its initial linear shape to a circular one while passing through the esophageal stenosis. The operation time, the success rate of the deformation self-assembly of Y-Z DSAMARs, and the successful MCA for esophageal stenosis were recorded. We successfully obtained a trapezoidal magnetic unit. Ten such magnetic units can self-assemble into a ring after the hard guide wire is withdrawn. The success rates for both self-assembly deformation and esophageal stenosis anastomosis were 93.33%, while that for esophageal stenosis anastomosis with successful deformation was 100%. Y-Z DSAMARs exhibit remarkable deformation-controllable characteristics. Further optimization of the operational procedure and verification through animal experiments are needed before they can be clinically applied. |
| format | Article |
| id | doaj-art-c24d7916cfb948a68d4a7ab59c802b49 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-c24d7916cfb948a68d4a7ab59c802b492024-12-08T12:24:57ZengNature PortfolioScientific Reports2045-23222024-12-0114111210.1038/s41598-024-81856-3An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosisMiaomiao Zhang0Xuhe Zhao1Qiuye Zhong2Linxin Shen3Ruimin Gong4Yi Lyu5Xiaopeng Yan6Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong UniversityZonglian College, Xi’an Jiaotong UniversityZonglian College, Xi’an Jiaotong UniversityZonglian College, Xi’an Jiaotong UniversityZonglian College, Xi’an Jiaotong UniversityDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong UniversityAbstract Magnetic compression anastomosis (MCA) for esophageal stenosis requires the insertion of magnets through two channels, transoral and transgastrostomy. Herein, we designed a Y-Z deformable self-assembled magnetic anastomosis ring (Y-Z DSAMAR) for esophageal stricture anastomosis through the transoral passage only. We introduce a Y-Z DSAMAR and verify its feasibility for single-access esophageal stenosis anastomosis in isolated organs. We procured esophagi from 10 pigs. Next, we ligated the middle part of these esophagi with 7 − 0 silk to prepare an esophageal stenosis model. The linear Y-Z DSAMAR completed the deformation self-assembly and transitioned from its initial linear shape to a circular one while passing through the esophageal stenosis. The operation time, the success rate of the deformation self-assembly of Y-Z DSAMARs, and the successful MCA for esophageal stenosis were recorded. We successfully obtained a trapezoidal magnetic unit. Ten such magnetic units can self-assemble into a ring after the hard guide wire is withdrawn. The success rates for both self-assembly deformation and esophageal stenosis anastomosis were 93.33%, while that for esophageal stenosis anastomosis with successful deformation was 100%. Y-Z DSAMARs exhibit remarkable deformation-controllable characteristics. Further optimization of the operational procedure and verification through animal experiments are needed before they can be clinically applied.https://doi.org/10.1038/s41598-024-81856-3Magnetic surgeryMagnetic compression anastomosisEsophageal stenosisY-Z deformable self-assembled magnetic anastomosis ringsEsophageal anastomosis |
| spellingShingle | Miaomiao Zhang Xuhe Zhao Qiuye Zhong Linxin Shen Ruimin Gong Yi Lyu Xiaopeng Yan An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis Scientific Reports Magnetic surgery Magnetic compression anastomosis Esophageal stenosis Y-Z deformable self-assembled magnetic anastomosis rings Esophageal anastomosis |
| title | An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| title_full | An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| title_fullStr | An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| title_full_unstemmed | An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| title_short | An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| title_sort | isolated organ feasibility study of deformable self assembled magnetic anastomosis rings for esophageal stenosis anastomosis |
| topic | Magnetic surgery Magnetic compression anastomosis Esophageal stenosis Y-Z deformable self-assembled magnetic anastomosis rings Esophageal anastomosis |
| url | https://doi.org/10.1038/s41598-024-81856-3 |
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