Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism

Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism

Developmental and epileptic encephalopathies (DEEs), a class of devastating neurological disorders characterized by recurrent seizures and exacerbated by disruptions to excitatory/inhibitory balance in the brain, are commonly caused by mutations in ion channels. Disruption of, or variants in, FGF13...

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Bibliographic Details
Main Authors: Susan Lin, Aravind R Gade, Hong-Gang Wang, James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H Schwartz, Anjali Rajadhyaksha, Geoffrey S Pitt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
sodium channels
epilepsy
inhibitory interneuron
Online Access:https://elifesciences.org/articles/98661
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