Which Dermal Filler is Better for Penile Augmentation for Aesthetic Purposes? A Prospective, Single-Surgeon Study Based on Real-World Experience
Purpose: Several types of dermal fillers have been recently introduced and used for penile augmentation (PA). However, few studies have compared outcomes after the injection of different fillers. This study aimed to compare the clinical outcomes of hyaluronic acid (HLA), polylactic acid (PLA), and...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society for Sexual Medicine and Andrology
2025-04-01
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| Series: | The World Journal of Men's Health |
| Subjects: | |
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| Summary: | Purpose: Several types of dermal fillers have been recently introduced and used for penile augmentation (PA). However, few
studies have compared outcomes after the injection of different fillers. This study aimed to compare the clinical outcomes of
hyaluronic acid (HLA), polylactic acid (PLA), and polymethyl methacrylate (PMA) filler injections, which are the most commonly
used for aesthetic purposes.
Materials and Methods: This prospective study was conducted for 24 weeks after a filler injection by a surgeon between
March 2017 and December 2021. Healthy adult men complaining of small penis were enrolled. Penile girth, satisfaction,
and injection-associated adverse events (AEs) were assessed at baseline and 4, 12, and 24 weeks after injection.
Results: Of the 301 men who received filler injections, 125, 134, and 42 received HLA, PLA, and PMA fillers, respectively.
The augmentation effect was in the order of PMA, HLA, and PLA, respectively, at 24 weeks (PMA vs. HLA, p<0.001; HLA
vs. PLA, p=0.006). Satisfaction levels increased significantly at 24 weeks in all groups (each with p<0.001). However, the
increase in satisfaction levels was smaller in the PMA group (PMA vs. HLA or PLA, p<0.05, for both penile appearance
and sexual life). No serious or systemic AEs were recorded. Filler injection-associated local AEs in the HLA, PLA, and PMA
groups occurred in 9 (7.2%), 16 (11.9%), and 6 (14.3%) men, respectively. There was no significant difference in AEs among
the groups (p=0.299).
Conclusions: The augmentative effect was greater in the PMA group than in the HLA and PLA groups, whereas the increase
in satisfaction levels was smaller in the PMA group. Our study demonstrated the clinical course of different types of fillers
and suggests that the filler type should be selected after detailed counseling considering individual characteristics and preferences. |
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| ISSN: | 2287-4208 2287-4690 |