Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives
Abstract Fibrous hydrogels (FGs), characterized by a 3D network structure made from prefabricated fibers, fibrils and polymeric materials, have emerged as significant materials in numerous fields. However, the challenge of balancing mechanical properties and functions hinders their further developme...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202408657 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841553179117879296 |
|---|---|
| author | Wen Luo Liujiao Ren Bin Hu Huali Zhang Zhe Yang Lin Jin Di Zhang |
| author_facet | Wen Luo Liujiao Ren Bin Hu Huali Zhang Zhe Yang Lin Jin Di Zhang |
| author_sort | Wen Luo |
| collection | DOAJ |
| description | Abstract Fibrous hydrogels (FGs), characterized by a 3D network structure made from prefabricated fibers, fibrils and polymeric materials, have emerged as significant materials in numerous fields. However, the challenge of balancing mechanical properties and functions hinders their further development. This article reviews the main advantages of FGs, including enhanced mechanical properties, high conductivity, high antimicrobial and anti‐inflammatory properties, stimulus responsiveness, and an extracellular matrix (ECM)‐like structure. It also discusses the influence of assembly methods, such as fiber cross‐linking, interfacial treatments of fibers with hydrogel matrices, and supramolecular assembly, on the diverse functionalities of FGs. Furthermore, the mechanisms for improving the performance of the above five aspects are discussed, such as creating ion carrier channels for conductivity, in situ gelation of drugs to enhance antibacterial and anti‐inflammatory properties, and entanglement and hydrophobic interactions between fibers, resulting in ECM‐like structured FGs. In addition, this review addresses the application of FGs in sensors, dressings, and tissue scaffolds based on the synergistic effects of optimizing the performance. Finally, challenges and future applications of FGs are discussed, providing a theoretical foundation and new insights for the design and application of cutting‐edge FGs. |
| format | Article |
| id | doaj-art-c1e0ad1dff8946f7b854ce878f655fb7 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-c1e0ad1dff8946f7b854ce878f655fb72025-01-09T11:44:45ZengWileyAdvanced Science2198-38442025-01-01121n/an/a10.1002/advs.202408657Recent Development of Fibrous Hydrogels: Properties, Applications and PerspectivesWen Luo0Liujiao Ren1Bin Hu2Huali Zhang3Zhe Yang4Lin Jin5Di Zhang6International Joint Research Laboratory for Biomedical Nanomaterials of Henan Henan Key Laboratory of Rare Earth Functional Materials Zhoukou Normal University Zhoukou 466001 P. R. ChinaThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 P. R. ChinaInternational Joint Research Laboratory for Biomedical Nanomaterials of Henan Henan Key Laboratory of Rare Earth Functional Materials Zhoukou Normal University Zhoukou 466001 P. R. ChinaInternational Joint Research Laboratory for Biomedical Nanomaterials of Henan Henan Key Laboratory of Rare Earth Functional Materials Zhoukou Normal University Zhoukou 466001 P. R. ChinaThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 P. R. ChinaInternational Joint Research Laboratory for Biomedical Nanomaterials of Henan Henan Key Laboratory of Rare Earth Functional Materials Zhoukou Normal University Zhoukou 466001 P. R. ChinaDepartment of General Surgery (Colorectal Surgery) Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangdong Institute of Gastroenterology Biomedical Innovation Center, The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou 510655 P. R. ChinaAbstract Fibrous hydrogels (FGs), characterized by a 3D network structure made from prefabricated fibers, fibrils and polymeric materials, have emerged as significant materials in numerous fields. However, the challenge of balancing mechanical properties and functions hinders their further development. This article reviews the main advantages of FGs, including enhanced mechanical properties, high conductivity, high antimicrobial and anti‐inflammatory properties, stimulus responsiveness, and an extracellular matrix (ECM)‐like structure. It also discusses the influence of assembly methods, such as fiber cross‐linking, interfacial treatments of fibers with hydrogel matrices, and supramolecular assembly, on the diverse functionalities of FGs. Furthermore, the mechanisms for improving the performance of the above five aspects are discussed, such as creating ion carrier channels for conductivity, in situ gelation of drugs to enhance antibacterial and anti‐inflammatory properties, and entanglement and hydrophobic interactions between fibers, resulting in ECM‐like structured FGs. In addition, this review addresses the application of FGs in sensors, dressings, and tissue scaffolds based on the synergistic effects of optimizing the performance. Finally, challenges and future applications of FGs are discussed, providing a theoretical foundation and new insights for the design and application of cutting‐edge FGs.https://doi.org/10.1002/advs.202408657conductivityECM‐likefibrous hydrogelsmechanicalstimulus |
| spellingShingle | Wen Luo Liujiao Ren Bin Hu Huali Zhang Zhe Yang Lin Jin Di Zhang Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives Advanced Science conductivity ECM‐like fibrous hydrogels mechanical stimulus |
| title | Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives |
| title_full | Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives |
| title_fullStr | Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives |
| title_full_unstemmed | Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives |
| title_short | Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives |
| title_sort | recent development of fibrous hydrogels properties applications and perspectives |
| topic | conductivity ECM‐like fibrous hydrogels mechanical stimulus |
| url | https://doi.org/10.1002/advs.202408657 |
| work_keys_str_mv | AT wenluo recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT liujiaoren recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT binhu recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT hualizhang recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT zheyang recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT linjin recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives AT dizhang recentdevelopmentoffibroushydrogelspropertiesapplicationsandperspectives |